Third, the earliest appearance of C4.4A in embryogenic development of the esophagus occurs at E15.5 [12], corresponding to the initiation of esophageal transdifferentiation from a columnar to a
stratified squamous epithelium [45].
In the nonglandular part, the
stratified squamous epithelium (arrow) was cornified and the circular muscle (CM) was developed.
Histopathology showed thyroglossal duct cyst with
stratified squamous epithelium infiltrated by papillary cells.
Mitosis and differentiation in the
stratified squamous epithelium of the rat esophagus.
Anti-CK5/6 strongly stained the transition area from
stratified squamous epithelium to neoplasia; the squamous solid component and the glandular structures were moderately stained.
(3) Histopathologically, KOTs are characterized by a connective tissue capsule lined with parakeratinized
stratified squamous epithelium of 5-8 cell layers.
(1) Evidence points to this as a metaplastic condition in reaction to ulceration and re-epithelialisation, the columnar epithelium replacing the normal
stratified squamous epithelium. (2) Only specialised columnar epithelium consisting of a villiform growth pattern containing columnar, goblet, Paneth and endocrine cells (i.e.
Smejkal, "Field cancerization in oral
stratified squamous epithelium: clinical implications of multicentric origin," Cancer, vol.
Histologically, the specimen displayed both endophytic and exophytic morphology, comprising of warty papillomatous projections lined by variably atypical
stratified squamous epithelium and overlying hyperkeratosis and parakeratin.
(1) Oral epithelium is classified into three types based on their morphology and specific pattern of differentiation: keratinized
stratified squamous epithelium (masticatory mucosa distributed in hard palate and gingiva), non-keratinized
stratified squamous epithelium (buccal mucosa, labial mucosa) and specialized mucosa (dorsal surface of the tongue).
Stratified squamous epithelium with sebaceous and sweat glands, hair shafts, calcification, few bony spicules and bone marrow elements were all demonstrated.