17] It is usually solitary and has relative hypocellularity with a prominent feature that thick collagen bundles are arranged in a storiform
Histopathological examination of Case 1 showed that inflammatory cell infiltration consisting largely of lymphocytes and plasma cells on a background comprised of fibrous interstices with fibrosis, fibroblast proliferation, storiform
fibrosis and obliterative phlebitis [a (200x)-b (400x)].
plasma cells and often increased eosinophils; (2) a storiform
pattern of fibrosis; and (3) obliterative vasculitis.
The cellular fibrostroma consists of plump fibroblastic spindle cells arranged in fascicular to storiform
pattern with basophilic nuclei.
Immunoglobulin G4-related systemic disease (IgG4-RSD) is a recently emerging disorder characterized by swelling lesions with storiform
fibrosis and lymphoplasmacytic infiltration enriched with IgG4-positive plasma cells.
IgG4-RD is an immune-mediated fibroinflammatory condition characterized histopathologically by three hallmark features in involved tissue: obliterative phlebitis, storiform
fibrosis, and a dense lymphoplasmacytic infiltrate.
1,6] Histopathology confirms the diagnosis, yet scenario may sometimes get convoluted microscopically - marked by chronic inflammation, necrosis, haemorrhage, infiltration into serosa, foamy macrophages, spindle-shaped xanthoma cells in storiform
pattern and exuberant fibrosis.
A 4 mm biopsy of a skin nodule on his trunk revealed an atrophic epidermis and a grenz zone below the epidermis with a nodular infiltrate located mostly in the mid dermis, but extending until the subcutis and composed mainly by a spindle-shaped histiocytes arranged in a storiform
Microscopic assessment of the sacrococcygeal mass showed a hypercellular tumour composed of plump spindle cells with elongated nuclei and abundant eosinophilic cytoplasm arranged in storiform
and herringbone patterns in areas.
The fibrocytes were monomorphous, elongated and spindle shaped, arranged in a storiform
Rare mitotic figures were observed; architecture was focally storiform
(similar to that of dermatofibrosarcoma).
Fibroblastic meningioma containing spindle-shaped tumor cell in storiform
and fascicular pattern, and sometimes containing crystalline structure rich in tyrosine is noted.