Nonossifying fibroma contains fascicles of spindle cells arranged in a storiform
pattern; however, the neoplastic cells lack the deeply eosinophilic cytoplasm and rhabdomyoblast-like cells characteristic of PH.
SaC has a biphasic nature comprising of the sarcomatous spindle cells which are arranged in various patterns such as fascicles as seen in our case and also storiform
pattern, and epithelial component.,, Tumor cells show prominent eosinophillic nucleus with high mitotic counts of 3-8/hpf with bizarre atypical mitosis. The epithelial component may be in the form dysplasia or carcinoma-in-situ or component of the infiltrating tumor.
 Histologically, DFSP is characterised by a fibroblastic proliferation of tumour cells arranged around a central storiform
The tumour cells are composed of uniform population of monomorphic spindle cells arranged in storiform
pattern with mitotic figures not exceeding 5 per 10 HPF.13 The American Joint Committee on Cancer has not established a staging system for Dermatofibrosarcoma Protuberans (DFSP).
Final pathological examination showed a tumour composed of malignant spindle cells (figure 2 and 3; spindle shaped cells are arranged in storiform
pattern) that are CD 34 positive (Figure 4; diffuse expression of CD34) and CK, S100, ER, PR and CD 68 negative which suggest the diagnosis of low-grade dermatofibrosarcoma protuberans.
The mainstay of diagnosis, regardless of the organ involved, is the identification of histopathologic features, which include dense lymphoplasmacytic inflammation, storiform
fibrosis, obliterative phlebitis, and demonstration of dominance of IgG4-positive plasma cells (9).
have suggested that aberrant NET formation may be correlated with the pathogenesis of DM, PM, and the complication of interstitial lung disease (ILD). NET production was increased or degradation decreased in DM/PM patients, and the lowest NET degradation was observed in DM/PM patients with ILD. Recently, the role of NET formation also has been tested in IgG4-related AIP that is characterized by massive infiltration of IgG4-expressing cells into the pancreas, increased serum IgG4 levels, and storiform
Microscopic examination of urethral MMs demonstrates a wide histologic spectrum with diffuse, nested, fascicular and storiform
patterns of pleomorphic cells .
Classification of this tumor type has been debated since it was first described as MFH in the 1960s, characterized as histiocytes and fibroblasts arranged in a storiform
or cartwheel-like pattern.
The most common patterns are storiform
, epithelioid, fibrosarcomatous, or patternless pattern.
Common features of IgG-RD include multiple organ involvements (which have swellings resembling tumors), fibrosis, tissue infiltrates (which are positive for IgG4 positive plasma cells), and a classical pathological form of storiform
In addition, the proliferation pattern of the mesenchymal cells was storiform