storage pool diseases
storage pool diseasesMetabolic disease A group of platelet disorders caused by defects of platelet granules, divided into
1. α granule storage pool disease. See Gray platelet syndrome and.
2. Dense granule deficiency or delta-storage pool disease Clinical Moderate bleeding Lab ↑ Bleeding time, ↓ platelet ADP content, ↓ serotonin levels Treatment Hemostasis with platelet transfusions, cryoprecipitate, desmopressin acetate–DDAVP, which releases von Willebrand factor from storage sites.