stomatocyte

stomatocyte

 [sto´mah-to-sīt]
an abnormal red blood cell in which a slit or mouthlike area replaces the normal central circle of pallor, often due to edema.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

sto·ma·to·cyte

(stō'mă-tō-sīt),
A red blood cell that exhibits a slit or mouth-shaped pallor rather than a central one on air-dried smears; for example, Rh null cells.
[stomato- + G. kytos, cell]
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
(a) Data set Training Validation Test Normal 728 81 203 Echinocyte 226 25 63 Dacrocyte 64 7 18 Schistocyte 546 61 152 Elliptocyte 66 7 18 Acanthocyte 120 13 33 Target cell 523 58 145 Stomatocyte 79 9 22 Spherocyte 173 19 48 Overlap 166 18 46 (a) Cells were randomly distributed 80:20 between training and test sets, respectively.
Caption: Figure 1: Phase images of erythrocytes, taken using LIM (oX, oY: erythrocyte sizes, [micro]m; oZ: optical path difference (OPD), nm): (a) erythrocyte from a healthy donor (discocyte); (b) erythrocyte from a MI patient before treatment (spherocyte); (c) erythrocyte from a SA patient before treatment (stomatocyte); (d) erythrocyte from a MI patient after treatment (stomatocyte).
Moreover, microscopic examination of blood films obtained from naturally infected cases showed presence of parasite and various morphological changes in cells such as stomatocyte, hypochromia and polychromia.
The spontaneous curvature model, developed by Deuling and Helfrich [1], described the stomatocyte and discocyte shapes of the red blood cells for the first time.
Stomatocyte Haemolysis: Stomatocytes are RBCs with a defect in their membranes that causes the cells to assume a mouth or stoma-like shape.
Clinically, [Rh.sub.null] individuals present with a compensated hemolytic anemia, and examination of the peripheral blood smear reveals the characteristic presence of stomatocytes. Because of the association with RhAG, [Rh.sub.null] cells lack all LW BGAs and have reduced glycophorin B (S and s antigens); yet, expression of the Diego system antigens are unaffected (Band 3).
Liver disease and excess ethanol consumption are common causes of macrocytosis with the blood smear usually showing round rather than oval macrocytes and lacking hypersegmented neutrophils; target cells and stomatocytes may also be present.
Blood smears show variable numbers of stomatocytes, but usually less than 10% [1]; HX is characterized by a propensity to iron overload [4].
Another set of agents, including cationic amphipaths, low salt, low pH, and cholesterol depletion, induces concave shapes, called stomatocytes. Further loading with both types of agents induces budding off the membrane, resulting in spherical bodies.
Non-spiculated variants include target cells, ovalocytes and stomatocytes. Spiculated red cells have at least one pointed projection from the cell surface [30].
The effect on morphology of erythrocytes by contrast media has also been studied [64, 65], with formation of echinocytes and stomatocytes observed upon incubation of erythrocytes with contrast media which may have a negative effect on the rheology of the blood [41].