stimulon


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stimulon

(stĭm′ū-lŏn″)
A cluster of genes whose transcription is modified by a single stimulus.
References in periodicals archive ?
Immuno-oncology company Agenus Inc (NASDAQ:AGEN) stated on Wednesday that the US Centers for Disease Control and Prevention's (CDC) Advisory Committee on Immunization Practices (ACIP) has voted in favor of three recommendations for the Shingrix (Zoster Vaccine Recombinant, Adjuvanted) vaccine with QS-21 Stimulon for the prevention of shingles (herpes zoster), a virus called varicella zoster, which is also known as the chicken pox virus.
The Herpes Zoster subunit vaccine (Shingrix) containing QS-21 Stimulon is recommended for herpes zoster and related complications for immunocompetent adults age 50 year and older; herpes zoster and related complication for immunocompetent adults who previously received Zoster Vaccine Live (Zostavax); as well as preferred over Zoster Vaccine Live (Zostavax) for herpes zoster and related complications.
Our proprietary position is further strengthened with the European Patent Office's decision to uphold this key European patent, which together with our existing United States patents, provides broad protection for our Stimulon technology," said Alison Taunton-Rigby, PhD, president and chief executive officer of Aquila.
have licensed QS-21 and other Stimulon adjuvants for use in products targeted at a variety of human diseases.
The addition of QS-21 Stimulon helps enhance the vaccine's effectiveness by increasing immune response in older adults who often experience age-related decline in immunity.
Garo Armen, PhD, chairman and CEO, Agenus, stated: "We are delighted by the remarkable efficacy of SHINGRIX, containing our proprietary QS-21 Stimulon adjuvant and the public health benefit; this FDA approval marks a significant milestone for Agenus.
The addition of QS-21 Stimulon, an immune-potent adjuvant that helps the body generate antibodies and T cells, improves the vaccine's effectiveness by boosting immune response in older adults who often experience age-related decline in immunity.
Concurrently, QS-21 Stimulon is being evaluated in 16 additional vaccine candidates currently undergoing clinical study and is a potential source of capital to help fund development of Agenus' checkpoint modulator product candidates.
It includes Agenus's QS-21 Stimulon adjuvant, a component of GSK's novel adjuvant system AS15.
19 October 2011 - Agenus Inc (NASDAQ:AGEN), a specialist in the development of therapeutic vaccines for cancer and infectious diseases, announced on Tuesday positive results of a Phase III trial of GlaxoSmithKline (LONGSK) Biologicals' RTS,S malaria vaccine candidate, which contains Agenus's QS-21 Stimulon adjuvant.