stilbestrol


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di·eth·yl·stil·bes·trol (DES),

(dī-eth'il-stil-bes'trol), Avoid the misspelling/mispronunciation diethylstilbesterol.
A synthetic nonsteroidal estrogenic compound. Sometimes used as a postcoital antipregnancy agent to prevent implantation of the fertilized ovum. The first demonstrated transplacental carcinogen responsible for a delayed clear cell vaginal carcinoma in female offspring of mothers who took the drug during pregnancy when the drug was erroneously thought to prevent threatened abortion.
Synonym(s): stilbestrol
Farlex Partner Medical Dictionary © Farlex 2012

stilbestrol

(stĭl-bĕs′trôl′, -trōl′)
n.
DES.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
References in periodicals archive ?
In the OVX animals, the uterus weight of mice treated with stilbestrol was highly significantly heavier than those of vehicle- and formononetin-treated mice (p<0.01).
Occasionally [sic] a nauseated patient became worse on stilbestrol, but usually there was no relationship between the two."(91) During menopause, it is strongly suggested, women's bodies are out of control, so much so that attempts to control them can have unexpected consequences.
In the second questionnaire, experts were asked whether they had any "comments or theories" about the "possible mechanism by which Stilbestrol produce[d] nausea." In addition, they were asked the following: "Do you think that the mechanism by which Stilbestrol produces nausea and vomiting must be understood before Stilbestrol can be considered sufficiently safe to be made available to the medical profession generally?"
3; Sir Charles Dodds, "Stilbestrol and After," Scientific Basis of Medicine: Annual Review (1965): 1-16; "Chemotherapy in Gynaecology," The Lancet (14 Jan.
Papanicolaou, "Clinical Study of the Synthetic Estrogen Stilbestrol," Journal of the American Medical Association 12 (23 Dec.
Palestrol Restrol Stil-Rol Stilbal Stilbestrol Stilbestronate Stilbetin Stilbinol Stilboestroform Stilboestrol Stilboestrol DP.
In fact, DES is a stilbestrol derivative whose core structure is that of the plant product stilbene, of which 4-OH-stilbene was also found to be an active disruptor of ER and NodD signaling.
Effects of estradiol, stilbestrol, and some alkyl-carbonyl androstanes upon sex differentiation in the medaka, Oryzias latipes.
Association of the maternal stilbestrol therapy with tumor appearance in young women.