An adult-onset neurological disorder characterized by muscle spasms and progressive muscle stiffness.
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stiff-per·son syn·drome(stif'pĕr-sŏn sin'drōm)
A rare disorder manifested clinically by the continuous isometric contraction of many of the somatic muscles; contractions are usually forceful and painful and most frequently involve the trunk musculature, although limb muscles may be involved. This is an autoimmune disease, with circulating antibodies against the GABA-synthesizing enzyme and glutamic acid decarboxylase, among other types of antibodies present.
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