sticky ends


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sticky ends

Complementary single strands of DNA protruding from the ends of a DNA fragment as a result of the cleaving of each half of the double helix at different points near to each other. Sticky ends readily provide attachment points for other pieces of DNA or for further DNA synthesis.
Cohesive endsclick for a larger image
Fig. 113 Cohesive ends . Formation of recombinant cloning vector using cohesive ends.

cohesive ends

or

‘sticky’ ends

overlapping COMPLEMENTARY single strands at the termini of double-stranded DNA molecules that can stick the two ends of the molecule (or the ends of different molecules) together by COMPLEMENTARY BASE PAIRING. Cohesive ends are often generated by digesting DNA molecules with the same RESTRICTION ENZYME. Cohesive ends provide a means of sticking insert DNA to VECTOR in the construction of recombinant cloning vectors for GENE CLONING.

sticky ends

References in periodicals archive ?
The particles stuck only when they were held together for several minutes-a sufficient period for the sticky ends to find a binding partner on another particle.
Muir's group and Xu's have used this tactic to make proteins with sticky ends.
Stieg Larsson's muck-raking trilogy of corruption draws to a satisfactory conclusion with a series of vile threats and sticky ends - for the righteous and wicked alike.