steroidogenic acute regulatory protein

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steroidogenic acute regulatory protein

Abbreviation: StAR protein

A protein found within cells of the adrenal glands and gonads that stimulates the conversion of cholesterol into sex hormones, corticosteroids, and mineralocorticoids.

See also: protein

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References in periodicals archive ?

Hormonal regulation of messenger ribonucleic acid expression for steroidogenic factor-1, steroidogenic acute regulatory protein, and cytochrome P450 side-chain cleavage in bovine luteal cells.

Molecular & genetic factors contributing to insulin resistance in polycystic ovary syndrome

Research studies point out the existence of a binding site for steroidogenic acute regulatory protein in the promoter region of the EG-VEGF gene.

Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis

Of note, the reduction of testosterone levels was accompanied by decreased expression of steroidogenic acute regulatory protein (StAR) and 3(3[beta]-hydroxysteroid dehydrogenase (3[beta]-HSD), as well as increased levels of cytochrome P450 side chain cleavage (P450scc), in Leydig cells.

Benzo[a]pyrene reduces testosterone production in rat leydig cells via a direct disturbance of testicular steroidogenic machinery

Molecular pathology and mechanism of action of the steroidogenic acute regulatory protein, StAR.

Computational model of steroidogenesis in human H295R cells to predict biochemical response to endocrine-active chemicals: model development for metyrapone