The benefit of steroid therapy
is well established, 14, 15 however, the rate of relapse remains high, 10% to 12% in such patients.16-18 General guidelines exist for the dosage and duration of steroids.19, 20 In hospital, the dosages are generally at par with the recommendations, but the discharge dose depends upon the primary physician and it varies not only in the level of dosage but the duration of the dosage as well, which has led to a significant issue for the safety of patients.
Although steroid therapy
has been associated with adverse effects such as aseptic necrosis of the hip, these complications usually arise after longer periods (ie, months to years) of high-dose steroid therapy
with a mean cumulative dose much higher than what was used in our patient.
The analysis included 375 patients with chronic sinusitis and nasal polyps who were candidates for revision endoscopic sinus surgery because of persisting symptoms of nasal obstruction/congestion and recurrent bilateral nasal polyps despite ongoing topical steroid therapy
and a recent course of systemic steroids.
The patient did not have any associated loss of Factor VIII activity or ALT elevations seven weeks following initiation of the steroid therapy
(five weeks post vector infusion).
His clinical and audiological abnormalities disappeared with steroid therapy
. However, each test showed different time courses of improvement.
There have been many advances in the treatment of allergies over the last five years and most vets now use a combination of treatments to maintain the condition by using the smallest dose of steroid possible alongside other treatments as there are a lot of side effects associated with long-term steroid therapy
(4) Here we present two cases, one woman and one man, who developed acute CSCR while under systemic steroid therapy
for Behcet's disease.
(10) reported that whereas mild ISSNHL cases showed a tendency for spontaneous recovery, and moderate and severe cases responded well to steroid therapy
, profound and complete loss cases had poor recovery.
And once he reached a maintenance dose of allergy shots, he no longer needed high dose steroid therapy
for his eczema."
Home infusion therapy includes total parenteral nutrition, infusion antibiotic therapy, hydration therapy, IV steroid therapy
, chemotherapy, enteral therapy, and pain management.
Herein, a case of allopurinol-induced DRESS syndrome is presented in which the patient was resistant to steroid therapy
but responded to IVIG and pulse steroid treatment, as given in the literature.