Although rare, the life-threatening illness of acute steroid myopathy
causing rhabdomyolysis in patients on high-dose corticosteroids should be recognised by clinicians and sports medicine specialists.
Neuromuscular diseases and steroid myopathy
as a cause of ventilator failure were excluded by repetitive muscle stimulation tests and electromyography.
Because of presumed increase in lupus lung activity, she was treated with prednisone 40 mg daily which was tapered to 10 mg daily due the development of steroid myopathy
Side effects can range from gastrointestinal bleeding, steroid myopathy
, and mood and behavioral changes to hyperglycemia.
is a potential side effect of this treatment regimen; it may occur 4 to 6 weeks after therapy starts.
Rheumatologists are being summoned to intensive care units for a newly recognized problem that is known by two names: acute steroid myopathy
and critical illness myopathy.
In both cases, it is essential to consider the use of corticosteroids, especially because the first patient we presented had a history of steroid myopathy
Inhibition of experimental steroid myopathy
by blockade of glucocorticoid receptor a histological and biochemical study.
However, even a single low-dose epidural steroid injection can induce severe steroid myopathy
(Boonen, Van Distel, Westhovens, & Dequeker, 1995; Mitsui et al.
4) Risks of developing steroid myopathy
increase with cumulative dose or duration, as well as multiple doses per day.
In addition, steroid myopathy
can occur, causing weakness primarily to proximal muscles of the upper and lower extremities and neck, which is frequently confused with progressive neurological disease.
Musculoskeletal effects consist of steroid myopathy
, osteoporosis, weight gain and fat redistribution.