Steroid 5alpha-reductase | definition of steroid 5alpha-reductase by Medical dictionary
an enzyme that uses NADPH to reduce certain steroids (for example, the conversion of testosterone to dihydrotestosterone); a deficiency of this enzyme is associated with a form of male pseudohermaphroditism in which genetic males have male genitals as well as female external genitalia.
References in periodicals archive
New mutations, hotspots, and founder effects in Brazilian patients with steroid 5alpha-reductase
deficiency type 2.
deficiency in man: an inherited form of male pseudohermaphroditism.
of the Department of Surgical Research at Beckman Research Institute of the City of Hope has revealed that white mushrooms contain phytochemicals that inhibit the enzymes aromatase and steroid 5alpha-reductase
A prevalent missense substitution that modulates activity of prostatic steroid 5alpha-reductase