A condition often noted in the cornea of contact lens wearers. These lesions differ from infectious infiltrates in so much that the overlying epithelium is usually intact, there is typically little or no pain, and the lesions tend to be small (less than 1.5 mm). The lesions consist of subepithelial infiltrates of leukocytes. It is postulated that these lesions are an immune response to a specific antigen (likely contact lens or solution-related), and not related to a bacterial infection. Treatment is often supportive with cessation of contact lens wear. See corneal infiltrates.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann