sterile infiltrates

sterile infiltrates 

A condition often noted in the cornea of contact lens wearers. These lesions differ from infectious infiltrates in so much that the overlying epithelium is usually intact, there is typically little or no pain, and the lesions tend to be small (less than 1.5 mm). The lesions consist of subepithelial infiltrates of leukocytes. It is postulated that these lesions are an immune response to a specific antigen (likely contact lens or solution-related), and not related to a bacterial infection. Treatment is often supportive with cessation of contact lens wear. See corneal infiltrates.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann
References in periodicals archive ?
Also in the present study complications of CXL like secondary infection, temporary corneal haze, permanent scars, endothelial damage, sterile infiltrates, and herpes reactivation were not considered.
Peripheral sterile infiltrates were observed during follow-up in 8 eyes of 8 patients; these eyes were treated with topical steroid eye drops starting four times daily and gradually decreased according to clinical response to treatment.
Because the long-term use of steroids has potential side effects like cataract and glaucoma, they are recommended for acute exacerbations and cases of sterile infiltrates, applied in gradually tapering doses.
(3) Sterile infiltrates can occur in non contact lens wearers, usually concomitant with blepharitis.
Unfortunately, in the early stages MK can look very similar to a sterile infiltrate. MK can progress to vision loss very quickly, so it is important to identify sufferers at as early a stage as possible.