Thus, automated indices may prove superior to manual stereologic
estimates because the latter most often are performed on a sample of cells and not the entire lesion.
Stereologic estimates of mean nuclear size are of prognostic value, independent of clinical stage of disease.
Stereologic estimates of volume-weighted mean nuclear volume in colorectal adenocarcinoma: correlation with histologic grading, Dukes' staging, cell proliferation activity and p53 protein expression.
The combined use of immunohistochemistry and unbiased stereologic
methods will be interesting in establishing quantitative relationships among the diverse types of peptidergic nerves and neuroendocrine cells from rat prostate in postnatal development (Rodriguez et al.
In the present study we used established stereologic
methods (Mahood et al.
One week later, locomotor activity was redetermined, and brains were harvested for determinations of levels of catecholamines and stereologic assessment of numbers of DA neurons (Barlow et al.
Another explanation eliminated by stereologic assessments is that the number of T[H.
and autometallographic studies on the brains of these adult monkeys indicated that the persistence of inorganic Hg in the brain was associated with a significant increase in the number of microglia in the brain, whereas the number of astrocytes declined.
For this purpose, we evaluated locomotor activity across the course of exposure, whereas monoamine levels in striatum, prefrontal cortex, nucleus accumbens, and hypothalamus and stereologic cell counts of TH-positive (T[H.
The remaining tissue was postfixed in 4% paraformaldehyde for immunohistochemistry and stereologic counts.
study of the effects of varying the time between initiation and promotion on four histochemical markers in rat liver during hepatocarcinogenesis.
Using a stereologic
approach, we found that Aroclor 1221 caused a highly significant down-regulation of the number of ER-[beta]-expressing cells in the AVPV, but had no effect in the SON.