stent thrombosis


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stent thrombosis

A blood clot that forms inside a device inserted into a blood vessel to keep that vessel open.

Patient Care

Stents are deployed in completely obstructed or partially blocked arteries to keep blood flowing through them to the organs they supply. When this blood flow stops due to clotting within the stent, the organ may become ischemic and die. To reduce the risk of clotting within a stent, patients use antiplatelet drugs, like aspirin, dipyridamole, or clopidogrel, and medications to lower serum lipid levels. Tobacco cessation, and healthy lifestyle changes (eating lighter, exercising regularly) may also be helpful.

See also: thrombosis
References in periodicals archive ?
Lack of association between dual antiplatelet therapy use and stent thrombosis between 1 and 12 months following resolute zotarolimus-eluting stent implantation.
The target lesion revascularization rate remained constant at four percent, with no new MACE events, and no late stent thrombosis.
The evidence indicates late stent thrombosis can unpredictably occur long after the prescribed period of protection with clopidogrel plus aspirin is over, he added.
The results showed that the pooled rate of stent thrombosis was 0.
Involving more than 8,700 patients at 196 centers in 36 countries across five continents, PROTECT was initiated to study the occurrence of a rare but serious adverse event known as stent thrombosis the formation of a blood clot inside the stent, which serves as a scaffold to keep the artery open.
Under the new Dublin/Academic Research Consortium (ARC) definition of late-stent thrombosis (blood clotting events in stents), which was developed to eliminate variability in the definitions across various drug-eluting stent trials, the late stent thrombosis rate with XIENCE V in the SPIRIT II trial out to one year was zero percent for XIENCE V (0/220 patients treated with XIENCE V) and 1.
Key endpoints of the study include assessments of safety -- MACE and stent thrombosis (blood clot formation) rates -- at 30, 180 and 270 days, with an annual follow-up for up to five years, and successful deployment of the bioabsorbable drug-eluting stent.
Some of the most exciting of the drug-eluting stent platforms working through the developmental pipeline have the potential to curb the vexing problem of late stent thrombosis, Dr.
Stent thrombosis is a potentially devastating complication of coronary artery stenting, and significant uncertainty currently exists amongst clinicians worldwide regarding the risks of stent thrombosis as compared to the potential bleeding risks associated with prolonged dual antiplatelet therapy," said Professor Meredith.
In addition, XIENCE V demonstrated a 77% lower rate of stent thrombosis, defined as definite or probable according to ARC (0.
Abbott also presented new positive nine-month safety data from the SPIRIT II trial, which showed no additional occurrences of MACE (Major Adverse Cardiac Event) or stent thrombosis between six and nine months.
4% Target Lesion Failure (TLF), the lowest reported TLF in a contemporary US pivotal study and a 0% rate of late stent thrombosis at 12 months, according to the companies.