Jessica has experienced numerous benefits as a result of the stem cell mobilization
These proposals supersede several existing patents on stem cell mobilization
This study involving human stem cell mobilization
was triggered by a few cases of empirical evidence that consumption of an extract from AFA, enriched for the LSL, resulted in an unexpected extent of recovery after traumatic injuries to the central nervous system.
Clinical impact and resource utilization after stem cell mobilization
failure in patients with multiple myeloma and lymphoma.
23, 2014 -- BioLineRx (BLRX) has received notice from the FDA confirming an Orphan Drug Designation of BL-8040 as a treatment for stem cell mobilization
, in addition to the Orphan Drug Designation previously granted to BL-8040 as a treatment for acute
Standard of care for patients with refractory or relapsing disease after initial therapy consists of a salvage therapy comprising a conventional chemotherapy regimen usually followed by stem cell mobilization
and subsequent high-dose chemotherapy along with autologous stem cell transplantation.
The CXCR4/SDF-1 axis has been shown to play a role in stem cell mobilization
, vasculogenesis, tumor growth and metastasis.
The first approved and marketed drug is plerixafor (AMD3100), a small molecule inhibitor of the CXCR-4/SDF-1 axis, used for stem cell mobilization
Frank Morich, Chief Executive Officer of NOXXON, commented: "Based on exceptionally positive pre-clinical data, we strongly believe that, NOX-A12 has the potential to become an improved alternative for hematopoietic stem cell mobilization
The presentation titled, "Chemokine regulation of hematopoietic stem cell mobilization
and angiogenesis" will be delivered on Friday, October 23, 2009 on behalf of OncoCyte Corporation and BioTime Asia.
In the CXCR4 project, the in vivo results achieved with Ascent's novel lipopeptide Pepducins were at least as efficacious as those seen with Mozobil[R], a small molecule drug marketed by Genzyme which was recently approved for stem cell mobilization
prior to bone marrow transplantation.
Biothera is currently conducting a Phase I/II clinical trial for stem cell mobilization
and has several Phase II cancer trials planned for 2007.