steatosis


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degeneration

 [de-gen″ĕ-ra´shun]
deterioration; change from a higher to a lower form, especially change of tissue to a lower or less functionally active form. When there is chemical change of the tissue itself, it is true degeneration; when the change consists in the deposit of abnormal matter in the tissues, it is infiltration. adj., adj degen´erative.
caseous degeneration caseation (def. 2).
cerebromacular degeneration (cerebroretinal degeneration)
1. degeneration of brain cells and of the macula retinae, as occurs in tay-sachs disease.
2. any lipidosis with cerebral lesions and degeneration of the retinal macula.
colloid degeneration degeneration with conversion of the tissues into a gelatinous or gumlike material.
cystic degeneration degeneration with formation of cysts.
fatty degeneration deposit of fat globules in a tissue.
fibroid degeneration degeneration of a leiomyoma with subsequent fibrosis.
hepatolenticular degeneration Wilson's disease.
hyaline degeneration a regressive change in cells in which the cytoplasm takes on a homogeneous, glassy appearance; also used loosely to describe the histologic appearance of tissues.
hydropic degeneration a form in which the epithelial cells absorb much water.
lattice degeneration of retina a frequently bilateral, usually benign asymptomatic condition, characterized by patches of fine gray or white lines that intersect at irregular intervals in the peripheral retina, usually associated with numerous, round, punched-out areas of retinal thinning or retinal holes.
macular degeneration see macular degeneration.
macular degeneration, congenital see stargardt's disease.
macular degeneration, Stargardt's stargardt's disease.
mucoid degeneration degeneration with deposit of myelin and lecithin in the cells.
mucous degeneration degeneration with accumulation of mucus in epithelial tissues.
myofibrillar degeneration damage to selective cardiac cells when surrounding interstitial cells, nerves, and capillaries remain viable.
myxomatous degeneration mucous degeneration.
spongy degeneration of central nervous system (spongy degeneration of white matter) Canavan disease.
subacute combined degeneration of spinal cord degeneration of both the posterior and lateral columns of the spinal cord, producing various motor and sensory disturbances; it is due to vitamin B12 deficiency and is usually associated with pernicious anemia. Called also Lichtheim's or Putnam-Dana syndrome.
wallerian degeneration fatty degeneration of a nerve fiber that has been severed from its nutritive source.
Zenker's degeneration Zenker's necrosis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ad·i·po·sis

(ad-i-pō'sis),
Excessive local or general accumulation of fat in the body.
Synonym(s): lipomatosis, liposis (1) , steatosis (1)
[adipo- + G. -osis, condition]
Farlex Partner Medical Dictionary © Farlex 2012

steatosis

(stē′ə-tō′sĭs)
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

steatosis

A pattern of reversible cell injury resulting from hypoxia, toxic or metabolic insults, diabetes mellitus, obesity, and protein malnutrition, which consists of an accumulation of droplets of triglcerides/neutral fat in various solid organs—classically, the liver—and most common in alcoholics in whom the changes regress with abstention from alcohol. Fatty changes may also occur in other organs (e.g., heart, muscle, kidney).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

ad·i·po·sis

(ad'i-pō'sis)
Excessive local or general accumulation of fat in the body.
Synonym(s): lipomatosis, liposis (1) , steatosis (1) .
[adipo- + G. -osis, condition]

fat·ty de·gen·er·a·tion

(fat'ē dĕ-jen'ĕr-ā'shŭn)
Abnormal formation of microscopically visible droplets of fat in the cytoplasm of cells, as a result of injury.
Synonym(s): adipose degeneration, steatosis (2) .
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Nonalcoholic fatty liver disease: from steatosis to cirrhosis.
Hepatic steatosis and focal fat deposition are well-known clinical entities.
Differential therapeutic effects of crataegus aronia and simvastatin on the hepatocyte ultrastructure in hepatic steatosis. Int.
NASH is defined as the presence of both steatosis (5% of hepatocytes or more) and lobular inflammation with hepatocyte injury (e.g., ballooning), with or without fibrosis.
Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population.
Acquired and accumulated excessive TGs in hepatocytes may be considered as the first step of the 'two hits' in the progression of NAFLD.[32] Although considerable progress has been made in understanding the molecular mechanisms underlying hepatic steatosis,[33] satisfactory treatment modalities remain limited.
This increased carbohydrate load contributes to insulin resistance and associated hepatic steatosis. More importantly, obesity-associated dysbiosis causes intestinal inflammation, barrier defects, and sets off a cascade of inflammatory molecules including lipopolysaccharides, lipoprotein lipase, interleukin-1 (IL-1), and tissue necrosis factor-alpha (TNF-[alpha]) in hepatic tissue.
Results from an unpublished animal model in which mice were fed a high-trans-fat diet for 24 weeks showed that the mice developed steatosis by week 8 and NASH by week 24.
The influence of social, demographic and clinical characteristics (gender, age, path of infection, duration of infection, fibrosis degree, steatosis, presence of extrahepatic manifestations, repeated treatments, virus genotype and serum VL) on the success of antiviral therapy for CHC was examined.
Nineteen (16.8%) had significant inflammation (Grade 2-3), 9 (8.0%) had significant fibrosis (Stage 2-3) and Steatosis was seen in 65 (57.5%) cases.
Donor data included in analysis were donor age, body mass index (BMI), hepatitis B (HBV) status, hepatitis C (HCV) status, aspartate-aminotransferase (AST), alanine-aminotransferase (ALT), gamma-glutamyl transferase (GGT), international normalized ratio (INR), creactive protein (CRP), creatinine, sodium, history of diabetes mellitus, or smoking, cardiopulmonary resuscitation, cause of death, duration of intensive care unit (ICU) stay, signs for steatosis hepatis in ultrasonography, steatosis hepatis in histopathology report, and the allocation phase, i.e., whether the offered donor liver was procured or transplanted at all.