Stearyl-CoA desaturase | definition of stearyl-CoA desaturase by Medical dictionary
a protein complex that is key in the synthesis of unsaturated fatty acids; it introduces a double bond at Δ9; high dietary levels of unsaturated fatty acids decrease this enzyme's activity in the liver; a number of agents will induce this enzyme (for example, insulin, hydrocortisone, and triiodothyronine).
References in periodicals archive
Mechanism of rat liver microsomal stearyl-CoA desaturase
. Studies of the substrate specificity, enzyme-substrate interactions, and the function of lipid.
Transcriptional differences of four of these genes, adipocyte fatty acid binding protein (aP2), stearyl-CoA desaturase
(SCD), sterol regulatory element binding transcription factor 1 (SREBF1) and lipoprotein lipase (LPL) were confirmed using SYBR Green quantitative RT-PCR technology.