status spongiosus

sta·tus spon·gi·o·'sus

multiple fluid-filled spaces of microscopic size in the cerebral white matter; seen in certain hypoxic, toxic, and metabolic diseases.

status spongiosus

A nonspecific term for a wide variety of neuropathic conditions of autoimmune, hereditary, hypoxic, metabolic, toxic, viral and unknown origins.

Examples
Spongy degeneration, leukodystrophies, multiple sclerosis, etc.