status spongiosus

sta·tus spon·gi·o·'sus

multiple fluid-filled spaces of microscopic size in the cerebral white matter; seen in certain hypoxic, toxic, and metabolic diseases.

status spongiosus

A nonspecific term for a wide variety of neuropathic conditions of autoimmune, hereditary, hypoxic, metabolic, toxic, viral and unknown origins.

Examples
Spongy degeneration, leukodystrophies, multiple sclerosis, etc.
References in periodicals archive ?
Histologically, a moderate to marked status spongiosus of the nervous tissue was present in the CNS with a bilateral and symmetrical pattern affecting mainly the white matter.
D) Cerebral internal capsule with status spongiosus (Bar=500[micro]m).
In addition, parahippocampal and temporal cortices, including cortex of the superior temporal gyrus, were very profoundly atrophic with "status spongiosus" --a characteristic finding of FTLD with nearly complete neuronal loss, cortical thinning, a reactive vascular pattern, and reactive astrogliosis.