statin


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statin

(stăt′n)
n.
Any of a class of lipid-lowering drugs that reduce serum cholesterol levels by inhibiting a key enzyme involved in the biosynthesis of cholesterol.

statin

–statin

A popular term for a HMG-CoA reductase inhibitor, which ↓ cholesterol–eg, pravastatin, lovastatin, etc, which ↓ progression of ASHD/CAD, even in absence of ↑ cholesterol. See Atorvastatin, Cervastatin, Fluvastatin, Lovastatin, Pravastatin, Simvastatin.

statin

(stat'in) [ -stat + -in]
Any of the drugs of the class known as 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors. These drugs have powerful lipid-lowering properties. The names of drugs in this class all end in “-statin” (e.g., atorvastatin, pravastatin, rosuvastatin, and simvastatin). Drugs from this class reduce the risk of myocardial infarction and stroke. Synonym: HMG CoA enzyme inhibitor

Patient discussion about statin

Q. husband has horrible rash bil. below knees to his ankles. it is bright red yellow weeping cracks. On statins He has been on zocor for 15 years and we are so afraid this may have something to do with this drug. He has stopped taking the drug because the pain and weakness, and numbness in his legs is considerable

A. i looked up for side effects and i saw only "eczema" as a skin side effect. but it seems odd to me that after 15 years you got this kind of side effect. it should have appeared years ago. you know- it might be a very good idea to go and see a Dr... and not stopping a medication without warning..

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References in periodicals archive ?
Cleveland Clinic cardiologist Leslie Cho, MD, a world expert on statin intolerance, says there are three things you should try to ward off or minimize these problems, so you can continue taking advantage of these beneficial drugs.
Statins Should Be Your First Line of Defense Against Heart Disease: If you are statin-intolerant, there are several ways you can prevent or minimize side effects from these powerful cholesterol busters
Statins are known to cause muscle pains and it is thought one in 10 people may get them on a statin.
The vital stats on statins; Your guide to controversial drugs' ups & downs
The PS-matched group's "mortality rates were 88 (73-105) and 127 (114-142) for statin vs.
Statin use cut death and decompensation in cirrhosis
The researchers then determined which patients had been taking a statin and for how long before Parkinson's disease symptoms appeared.
Statins can bring out hidden Parkinson's disease
STATINS could prove a valuable weapon in the fight against breast cancer, experts say.
Statins 'could help fight breast cancer'
The findings raise the issue of extending statin prescriptions to anyone above the age of 40, but Dr Aung said that was probably not the way to go.
France : Statins Associated With Improved Heart Structure and Function
These two alarming studies have made it apparent that older patients on more intensive statin regimens are at the greatest risk of developing diabetes from their treatment.
Fighting statin-induced diabetes with CoQ10
Arya examined the association between the highest statin dose prescribed within 1 year of PAD diagnosis and rates of amputation and all-cause mortality at 1, 3, and 5 years of follow-up.
High-intensity statins found to reduce amputations, mortality in PAD
The right type of statin, for the right person, at the right time may provide an inexpensive means to decrease the burden of" Alzheimer's disease.
Statins May Lower Risk Of Developing Alzheimer's
There was no red-flag signal that would indicate that statin-induced cognitive decline is a significant side effect of long-term statin use.
You may benefit from statins even if your cholesterol level is normal
However, since the benefits of statins are more apparent from studies and patient experience, ezetimibe isn't given as a first-line therapy--instead it may be prescribed alongside a statin if statins alone aren't sufficient to lower cholesterol, or as an alternative for patients who cannot take a statin.
Newer cholesterol-lowering drugs may be an option if you can't take statins: older adults are at particular risk for statin side effects
Statin users have more calcium-containing coronary plaques than nonusers in clinical trials.
Statins and heart disease

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