start codon

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Related to start codon: stop codon

in·i·ti·a·ting co·don

the trinucleotide AUG (or sometimes GUG) that codes for the first amino acid in protein sequences, formylmethionine; the latter is often removed post-transcriptionally.
Synonym(s): start codon

start codon

A codon, AUG in eukaryotes and either GUG or UUG in bacteria, that signals the initiation of translation and the first amino acid in a polypeptide chain. Also called chain initiation codon.

start codon


a triplet in a chain of nucleic acids in mRNA that specifies the order in which amino acids are added. The codon triplet pairs with a sequence of three complementary nucleotides, called the anticodon, present in the anticodon arm of tRNA. Called also triplet. See also deoxyribonucleic acid.

start codon
see initiation codon.
stop c's
three codons, UAG, UAA and UGA, also referred to as amber, ochre and opal codons, in mRNA which terminate translation.
termination codon
see stop codons (above).
References in periodicals archive ?
Start codon targeted polymorphism for evaluation of functional genetic variation and relationships in cultivated peanut (Arachis hypogaea L.
Vitamin D receptor start codon polymorphism (FokI) is related to bone mineral density in healthy adolescent boys.
While both evidence the general rise in A's and decline in G's near the start codon, each lacks evidence of SD sequences.
If a 5'-proximal AUG triplet can serve as a sufficient translational initiation signal, then any AUG sequence positioned in this manner might conceivably be translated, mRNA conformation permitting, regardless of whether or not the utilized start codon is part of a legitimate open reading frame ending with one of the three possible termination codons.
The vitamin D receptor gene start codon polymorphism: A functional analysis of FokI variants.
dagger]) Assuming the third AUG of ORF2 is the start codon.
DO: Give each student group one START codon bead (methionine).
Polymorphism of vitamin D receptor gene start codon in patients with calcium kidney stones.
Promoters--Add additional noncoding letters before the start codon.
Sequence analysis revealed that these trace bands derived from a novel processed pseudogene, because any nucleotide alterations, including alterations at the translation start codon, were observed in the open reading frame (GenBank accession no.
Percentage identity shared between genes of 2 rabies virus strains from Sri Lanka, H-08-1320 and H-1413-09, by gene coding region * Gene H-1413-09 H-08-1320 Coding region Start codon, Coding region Start codon, stop codon stop codon N 71-1,423 ATG, TGA 71-1,423 ATG, TGA P 1,514-2,404 ATG, TGA 1,514-2,404 ATG, TGA M 2,496-3,104 ATG, TAA 2,497-3,105 ATG, TAA G 3,317-4,891 ATG, TGA 3,318-4,892 ATG, TGA L 5,407-11,793 ATG, TGA 5,408-11,794 ATG, TAA Gene % Identity Nucleotide Amino acid N 99.
Point out that there are two ways for the ligation to occur and that they occur with 50% probability (the gene could have been taped in with the start codon [ATG] adjacent to the T7 side of the plasmid or adjacent to the SP6 side of the plasmid).