SH2 domain(redirected from src-homology 2 domain)
SH2 domainA modular, circa-100-amino acid domain which binds to specific phospho-containing peptide motifs; SH2 is found in adaptors, kinases, phosphatase, Ras signalling, scaffolds, transcription, ubiquination. It is involved in cytoskeletal regulation, phospholipid second messenger signalling, and in signal regulation.
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