junction was scraped by rotating to 360 degrees and smeared onto a glass slide.
The authors conclude that this variant of low-grade squamous intraepithelial lesion (LSIL) originates from human papillomavirus (HPV)-infected cells at or proximal to the squamocolumnar
junction (SCJ) via "top-down and bottom-up differentiation," whereas LSILs reported as condylomata originate from HPV-infected cells more distal to the SCJ.
The major steps in cervical cancer development are: infection of the metaplastic epithelium at the squamocolumnar
junction, viral persistence, progression to cervical precancerous lesion, and then invasion through the basement membrane of epithelium.
The Working Group 1) developed recommended terminology for reporting findings in colposcopy practice in the United States and 2) defined the comprehensive documentation of the procedure as comprising cervix and squamocolumnar
junction visibility; acetowhitening; presence of a lesion; lesion visibility, size and location of lesion(s); vascular changes; other features; and colposcopic impression (TABLE 1).
After placing a speculum, the squamocolumnar
junction zone (SJZ) was previously identified.
When high-threshold was used then only well demarcated, opaque white areas near the squamocolumnar
junction (SCJ) were taken as positive; whereas in low-threshold criterion faint or ill-defined acetowhite anywhere and well-defined areas away from SCJ were also taken as positive.
One limitation, which is also a problem with current methods of visual inspection of the cervix, is lack of ability to see the squamocolumnar
In cases where the colposcopy did not reveal any lesions but was unsatisfactory, four-quadrant biopsies from the squamocolumnar
junction (SCJ) endocervical curettage may be taken.
Definite, angular, geographic, acetowhite lesions far away from the squamocolumnar
(8), where quality was measured according to the presence of elements of the squamocolumnar
80-100 units of Botulinum toxin A are injected in divided doses in all four quadrants at the level of the squamocolumnar
junction via endoscopic guidance.
They account for 90% of benign oesophageal strictures.76 Peptic strictures occur usually at the squamocolumnar
junction and measure 1-4 cm in length.