squalene


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squalene

 [skwa´lēn]
an unsaturated terpene that is an intermediate in cholesterol synthesis and occurs normally at low levels in blood plasma and at elevated levels in viral influenza; used as a vehicle for pharmaceuticals.

squa·lene

(skwā'lēn),
A hexaisoprenoid (triterpenoid) hydrocarbon; intermediate in the biosynthesis of cholesterol and other sterols and triterpenes; found in shark oil and in some plants.

squalene

(skwā′lēn′)
n.
An unsaturated aliphatic hydrocarbon, C30H50, that is the biosynthetic acyclic precursor to tetracyclic steroids such as cholesterol. It is widely found in animals, plants, and fungi and is present in high concentrations in shark liver oil and human sebum.

squa·lene

(skwā'lēn)
A natural nonaromatic hydrocarbon found in plants and animals; a precursor of steroids including cholesterol.
[L. squalus, shark]

squalene (skwäˑ·lēn),

n a popular traditional Asian remedy derived from the liver oil of sharks. Available as an over-the-counter agent, it is widely used for cosmetic purposes—particularly the regeneration of the skin. Oral administration of squalene has been associated with lipoid pneumonia due to aspiration.

squalene

an unsaturated terpene, which is an intermediate in cholesterol synthesis, and occurs normally at low levels in blood plasma and at elevated levels in viral influenza; used as a vehicle for pharmaceuticals.
References in periodicals archive ?
15) Macadamia oil also contains squalene, a natural emollient, (16,17) as well as vitamin E, which plays a crucial role in retaining moisture to reduce dryness.
The human surface reaction with ozone was then improved by modeling the reaction with squalene.
Olive powder contains high amounts of healthy compounds, including oleic acid, polyphenols, tocopherols, chlorophylls and squalene, which are beneficial for human health.
Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, secoiridoids, lignans and squalene.
This tends to support the concern by some researchers that squalene may increase the risk for autoimmune disorders in humans.
She was at Hay on Thursday to talk about the use of squalene, a substance found in sharks and used in the cosmetics industry.
Fluad is a trivalent, inactivated influenza vaccine that contains MF59 adjuvant, an oil-in-water emulsion containing squalene, polysorbate 80, and sorbitan trioleate.
From squalene the sterol skeleton is formed by ring closure, followed by the synthesis of cholesterol precursors and finally cholesterol.
11) Terbinafine inhibits squalene epoxidase, an enzyme involved in the synthesis of ergosterol, which gives terbinafine both fungicidal and fungistatic activity.
Surface-active substances and hydrocarbons such as squalene, decane, dudecane or specific isoparaffin have also been tried [9, 10].
The DOD made every attempt to deny that squalene was indeed an added contaminant in the anthrax vaccine administered to Persian Gulf War military personnel.
It contains the full spectrum tocotrienols as well as other phytonutrients such as plant squalene and phytosterols that are naturally extracted together with tocotrienols from virgin crude palm oil.