squalene


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squalene

 [skwa´lēn]
an unsaturated terpene that is an intermediate in cholesterol synthesis and occurs normally at low levels in blood plasma and at elevated levels in viral influenza; used as a vehicle for pharmaceuticals.

squa·lene

(skwā'lēn),
A hexaisoprenoid (triterpenoid) hydrocarbon; intermediate in the biosynthesis of cholesterol and other sterols and triterpenes; found in shark oil and in some plants.

squalene

(skwā′lēn′)
n.
An unsaturated aliphatic hydrocarbon, C30H50, that is the biosynthetic acyclic precursor to tetracyclic steroids such as cholesterol. It is widely found in animals, plants, and fungi and is present in high concentrations in shark liver oil and human sebum.

squa·lene

(skwā'lēn)
A natural nonaromatic hydrocarbon found in plants and animals; a precursor of steroids including cholesterol.
[L. squalus, shark]
References in periodicals archive ?
Lira, "Squalene synthase as a chemotherapeutic target in Trypanosoma cruzi and Leishmania mexicana," Molecular and Biochemical Parasitology, vol.
Bavavea, "Squalene synthase inhibitors: an update on the search for new antihyperlipidemic and antiatherosclerotic agents," Current Medicinal Chemistry, vol.
A surface reaction between ozone and squalene was represented with a first order rate constant of 2.0 [h.sup.-1].
There were nine (38.30%) moderately active antimicrobial compounds: 9.92% of phytol, 9.75% of 10-octadecenoic acid methyl ester, 5.46% of n-hexadecenoic, 5.27% of 9-hexadecenoic acid, 3.48% of octadecanoic acid methyl ester, 1.22% of heptadecanoic acid methyl ester, 1.14% of eicosanoic acid methyl ester, 1.04% of 9-hexadecenoic acid methyl ester (Z)-, and 1.02% of squalene. In addition there were 17 minor (11.23%) antimicrobial compounds (Table 1).
It should be noted that no statistically significant changes were observed in the squalene pattern during the study for any of the groups (Table 3).
The main components of the stems oil were nonacosane (23.26%), heptacosane (22.48%), hentriacontane (18.32%), octacosane (3.42%), triacontane (2.24%) and squalene (2.07%).,-damascenone, trans-,-ionone, 6,10,14- trimethyl-2-pentadecanone, docosane, tricosane, tetracosane, hexacosane, heptacosane, octacosane, squalene, nonacosane, triacontane and hentriacontane were common chemical constituents of essential oils.
(14) Not only did the experimental vaccines pose a threat to the troops' immune systems, the anthrax vaccination that they received contained squalene, an unapproved adjuvant that has since been linked to devastating autoimmune diseases.
Oleic acid (22.40 min.), stearic acid (22.97 min.) and squalene (34.34 min.) were also identified.
Those flakes contain skin oils, including cholesterol and "squalene," and are a major constituent of the dust that accumulates on tables and other surfaces in homes and offices.
It contains predominantly full spectrum tocotrienols and other phytonutrients such as tocopherols, plant squalene, phytosterols, coenzyme Q10 and mixed carotenoids that are naturally extracted alongside tocotrienols.