Results from the phase II IMPACT study of squalamine lactate
, based on an extract from the tissues of dogfish sharks, continue to show promise for AMD patients.
PLUS CARBOPLATIN IN TREATING PATIENTS WITH RECURRENT OR REFRACTORY STAGE III OR STAGE IV OVARIAN CANCER
These include such anti-angiogenic drugs as Squalamine Lactate
produced by Genaera Corp.
Genaera's other programs include squalamine lactate
for the treatment of cancer; interleukin-9 antibody, a potential treatment for asthma and associated respiratory disorders; LOMUCIN(TM), a mucoregulator to treat the overproduction of mucus and secretions involved in cystic fibrosis and other chronic respiratory diseases; and LOCILEX(TM) (pexiganan acetate), a topical antimicrobial (for which the Company is actively seeking a development partner).
is a first-in-class, anti-angiogenic small molecule being developed for exudative AMD and oncology.
DelConte will lead clinical research activities related to the development of trodusquemine (MSI-1436) for the treatment of obesity and squalamine lactate
for the treatment of cancer.