spontaneous tumor

spontaneous tumor

Oncology A neoplasm that arises in a control animal/person that is not exposed to a known carcinogen or tumor-promoting factor–eg, ionizing radiation, HPV
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Female mice bearing a spontaneous tumor about 10 mm in diameter were anaesthetized with an intra-peritoneal injection of 40 mg/kg Nembutal.
To overcome the limitations associated with the experimental brain metastasis model, several laboratories have adopted the use of spontaneous tumor models.
4,9) One recently published case describes spontaneous tumor regression, with significant size reduction during a period of 10 years.
It is well known that spontaneous tumor remissions are rarely, if ever, observed in recurrent head and neck cancers.
As a result, these animals are characterized by spontaneous tumor development.
Spontaneous tumor regression in a patient with metastatic gastric cancer.
Nasdaq: CALP), a leading provider of tools and services for drug discovery and life sciences research, today announced that the National Cancer Institute (NCI) has purchased Caliper's Quantum FX, a stand-alone microCT system for pre-clinical imaging, to study spontaneous tumor models in lung cancer.
In other cases, the rodent species and strains currently used in NTP chronic bioassays (F344/N rat and B6C3F1/N mouse) are suspected to be poor models because they either do not develop a specific type of tumor or have a high spontaneous tumor incidence.
Stimulation of the immune system has been considered a factor responsible for spontaneous tumor regression, (7,8) whereas suppression of the immune system may contribute to tumor induction.
Burton claimed that he offered these fractions "only after they [had] been fully tested for toxicity and efficacy in the strain of spontaneous tumor mice.
2004) noted the need for lifetime studies to characterize background or spontaneous tumor patterns and life spans (including those of the background strain) for these models.
On hospital day 6, the patient developed mental status changes accompanied by increasing serum potassium and creatinine levels due to spontaneous tumor lysis.

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