spongiform encephalopathy


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spon·gi·form en·ceph·a·lop·a·thy

an encephalopathy characterized by vacuolation within nerve and glial cells.

spongiform encephalopathy

n.
Any of a group of degenerative diseases of the brain characterized by the progressive formation of vacuoles in the cells of the cerebral cortex.

spon·gi·form en·ceph·a·lop·a·thy

(spŏn'ji-fōrm en-sef'a-lop'ă-thē)
An encephalopathy characterized by vacuolation within nerve and glial cells.

spongiform encephalopathy

One of a number of diseases of the nervous system featuring spongy degeneration of the grey matter of the brain, loss of nerve cells and overgrowth of the brain connective tissue cells (astrocytes). The effects are severe loss of function and death. These diseases are associated with an abnormal cellular inclusion called a prion and which can be diagnosed by locating specific defects within the prion gene. See also CREUTZFELDT-JAKOB DISEASE and KURU.

spongiform

resembling a sponge.

spongiform encephalopathy
a disease of the brain having the microscopic appearance of a sponge. The transmissible spongiform encephalopathies (TSEs) of animals and humans are Creutzfeldt-Jacob disease in humans and its variant, Gertstmann-Straussler-Scheinker disease in humans, kuru, fatal familial insomnia of humans, scrapie in sheep, goats and moufflon, transmissible encephalopathy of mink, chronic wasting disease of deer and elk, bovine spongiform encephalopathy (BSE), TSE of zoo ungulates, and feline spongiform encephalopathy. See also bovine spongiform encephalopathy, feline spongiform encephalopathy.
References in periodicals archive ?
Evaluation of the human transmission risk of an atypical bovine spongiform encephalopathy prion strain.
Professor Peter Smith, chair of the Spongiform Encephalopathy Advisory Committee, said, ``What this report shows is that mechanically recovered meat went into a variety of products, predominantly cheap burgers and cheap mince - products to which a high proportion of the population may have been exposed.
Unfortunately, this is only the beginning of our woes with spongiform encephalopathy in all its forms -- including canine and feline.
The link between cattle that are too sick or injured to stand or walk, and bovine spongiform encephalopathy (BSE or mad cow disease) has been clearly established," Marler said.
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are neurodegenerative disorders that include Creutzfeldt-Jakob disease (CJD) in humans, scrapie in sheep and goats, and bovine spongiform encephalopathy (BSE) in cattle.
The ban on so-called "downer" cows is designed to protect the food supply against beef coming from cattle infected with bovine spongiform encephalopathy, or mad cow disease.
Yes, only 1 cow out of the 20,000 tested has been discovered to have bovine spongiform encephalopathy (BSE).
Cotman's team and others have also found that ADDLs are similar in size and shape to prions, molecules that have been linked to the transmission of bovine spongiform encephalopathy ("mad cow disease") and other neurodegenerative diseases.
The move is designed to protect the company against any supply interruption resulting from the emergence of bovine spongiform encephalopathy, found in a diseased cow in northern Alberta and reported by officials May 20.
Already some scientists are questioning the findings of the Spongiform Encephalopathy Advisory Committee (Seac) about the link between BSE and vCJD and are also scaling down the number they expect to contract the disease (I hope they are correct on this).
2330 will provide $15 million for prevention and enforcement activities relating to bovine spongiform encephalopathy (BSE), and $10 million for adverse event monitoring and reporting activities.
The most commonly known TSE's are, Bovine Spongiform Encephalopathy ("BSE") in cattle, (commonly known as "mad-cow disease"), Scrapie in sheep, Chronic Wasting Disease ("CWD") in wild deer and elk and Creutzfeldt-Jakob Disease ("CJD") in humans.