spondylitis


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Related to spondylitis: spondylosis, spondylolysis

spondylitis

 [spon″dĭ-li´tis]
inflammation of the vertebrae, usually a serious and chronic disorder. It may be associated with tuberculosis of the bones, in which case it is called pott's disease. The vertebrae become eroded and collapse, causing kyphosis. Spondylitis may also be associated with other infectious diseases, such as brucellosis, in which the intervertebral disks and the vertebrae are affected and sometimes destroyed; this is one cause of ankylosing spondylitis, a particularly serious variety.
ankylosing spondylitis (Bekhterev's spondylitis) a form of rheumatoid arthritis that affects the spine, characterized by inflammation of the facet joints and inflammatory changes of the stabilizing ligaments of the spine (enthesopathy). It affects males almost exclusively. There is stiffening of spinal joints and ligaments, so that movement becomes increasingly painful and difficult. When it runs its full course, it results in bony ankylosis of the vertebral joints, which may extend to the ribs and limit the flexibility of the rib cage, so that breathing is impaired. Called also Marie-Strümpell disease or spondylitis and rheumatoid spondylitis.
Typical posture of patient with ankylosing spondylitis. From Copstead and Banasik, 2000.
Kümmell's spondylitis Kümmell's disease.
Marie-Strümpell spondylitis ankylosing spondylitis.
post-traumatic spondylitis Kümmell's disease.
rheumatoid spondylitis ankylosing spondylitis.

spon·dy·li·tis

(spon-di-lī'tis),
Inflammation of one or more of the vertebrae.
[spondyl- + G. -itis, inflammation]

spondylitis

(spŏn′dl-ī′tĭs)
n.
Inflammation of the vertebrae.

spondylitis

Orthopedics Inflammation of one or more vertebrae. See Ankylosing spondylitis.

spon·dy·li·tis

(spon'di-lī'tis)
Inflammation of one or more vertebrae.
[G. spondylos, vertebrae + G. -itis, inflammation]

spondylitis

Inflammation of any of the joints between the VERTEBRAE of the spine. This may occur in OSTEOARTHRITIS, RHEUMATOID ARTHRITIS, or, more specifically, in ANKYLOSING SPONDYLITIS.

Spondylitis

An inflammation of the spine.

Patient discussion about spondylitis

Q. Is ankylosing spondylitis genetically inherited?

A. It is known today that ankylosing spondylitis (spondyloarthritis) has a very strong genetic connection. It is not a disease inhertited by a single gene that is dominant, but certainly there is genetic predisposition in families (and a more detailed information- about 90% of the patients express the HLA-B27 genotype).

More discussions about spondylitis
References in periodicals archive ?
van Tubergen et al., "Lifestyle factors may modify the effect of disease activity on radiographic progression in patients with ankylosing spondylitis: a longitudinal analysis," Rheumatic Musculoskeletal Diseases Open, vol.
Yikai, "Serum functional dickkopf-1 levels are inversely correlated with radiographic severity of ankylosing spondylitis," Clinical Laboratory, vol.
The evaluation of comorbid diseases in patients with ankylosing spondylitis. Dicle Med J 2014;41:662-6.
'That's why it's hard to diagnose ankylosing spondylitis. If you look at the global prevalence, less than 1 percent is part of spondyloarthritis.'
Prospective meta-analysis of interleukin 1 gene complex polymorphisms confirms associations with ankylosing spondylitis. Ann Rheum Dis 2008; 67: 1305-9.
The use of vitamin D supplementation is vital for its role in autoimmunity, showing effectiveness in decreasing the risk of developing an autoimmune condition, such as ankylosing spondylitis. Vitamin D is shown to play a protective role in AS, signifying that without vitamin D, there can be permanent alterations of intestinal microbiota, causing inflammation.
Disease activity was evaluated using the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Ankylosing Spondylitis Disease Activity Index-CRP (ASDAS-CRP).18,19 Back mobility was evaluated with Bath Ankylosing Spondylitis Metrology Index (BASMI), and functional ability was evaluated with Bath Ankylosing Spondylitis Functional Index (BASFI).20
Gender differences in Iranian patients with ankylosing spondylitis. Clin Rheumatol 2015: 34(2):285-293.
Experts shared that 'Ankylosing Spondylitis - AS is a form of arthritis that primarily affects the spine.
This kind of arthritis -- known as ankylosing spondylitis -- can irreversibly damage and deform the joints when treatment is not provided early, which is why patients must report any symptoms to doctors, advised Dr Irena Khostanteen, consultant rheumatologist at the Health Shield Medical Centre in Abu Dhabi.
Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by inflammation and new bone formation at axial and peripheral entheseal sites [1].