split-mixed insulin dosing
split-mixed insulin dosing(split′mikst′)
A typical regimen divides the total daily dose of insulin by giving two thirds of the daily requirement in the morning and one third in the evening. The morning dose consists of two thirds of a long-acting agent and one third of an immediate or short-acting insulin or insulin analogue. The evening insulin dose is divided equally between long- and rapid-acting insulins. The evening dose is sometimes divided into two separate injections, with the rapid-acting insulin given before the evening meal and the long-acting insulin given at bedtime.