splenomegaly

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splenomegaly

 [sple″no-meg´ah-le]
enlargement of the spleen.
congestive splenomegaly splenomegaly secondary to portal hypertension, with ascites, anemia, thrombocytopenia, leukopenia, and episodic hemorrhage from the intestinal tract. Called also Banti's disease.
hemolytic splenomegaly enlargement of the spleen associated with hemolytic diseases of the blood.
siderotic splenomegaly splenomegaly with deposit of iron and calcium.

sple·no·meg·a·ly

, splenomegalia (splē'nō-meg'ă-lē, -mĕ-gā'lē-ă),
Enlargement of the spleen.
Synonym(s): megalosplenia
[spleno- + G. megas (megal-), large]

splenomegaly

(splē′nō-mĕg′ə-lē, splĕn′ō-)
n. pl. splenomega·lies
Enlargement of the spleen.

splenomegaly

Enlarged spleen Enlargement of spleen for any reason, which is usually a manifestation of underlying disease; the only specific finding in splenomegaly is dragging sensation in the upper right quadrant; megalic spleens may reach 4.0+ kg–eg, in agnogenic myeloid metaplasia
Splenomegaly
Congestion Cirrhosis, CHF, thrombosis of portal or splenic veins
Infection
• Bacteria Brucellosis, infective carditis agents, syphilis, TB, typhoid fever
• Fungi Histoplasmosis
• Parasites Echinococcosis, leishmaniasis, malaria, schistosomiasis, toxoplasmosis, trypanosomiasis
• Viruses CMV, EBV
Inflammatory/immune-related Rheumatoid arthritis, SLE
Hematopoietic disease/Lymphoid function
• Malignant Leukemias, eg ALL, CLL, myeloproliferative disorders–eg agnogenic myeloid metaplasia, CML, multiple myeloma, polycythemia vera; lymphomas–Hodgkin's disease, NHL
• Nonmalignant Hemolytic anemia, histiocytosis, ITP
Storage diseases Gaucher's disease, mucopolysaccharidosis, Niemann-Pick disease
Etc Amyloidosis, cysts, hypersplenism, metastases, primary tumors

sple·no·meg·a·ly

, splenomegalia (splēnō-megă-lē, -mĕ-gālē-ă)
Enlargement of the spleen.
Synonym(s): megalosplenia.
[spleno- + G. megas (megal-), large]

splenomegaly

SPLEEN ENLARGEMENT.

Splenomegaly

Abnormal enlargement of the spleen. Splenomegaly is a major diagnostic criterion of PV.

sple·no·meg·a·ly

, splenomegalia (splēnō-megă-lē, -mĕ-gālē-ă)
Enlargement of the spleen.
[spleno- + G. megas (megal-), large]