splenocyte


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splenocyte

 [sple´no-sīt]
the monocyte characteristic of splenic tissue.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

splenocyte

(splē′nō-sīt″) [″ + ″]
A monocyte found in the spleen or in splenic tissue.
Medical Dictionary, © 2009 Farlex and Partners
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A study with cyclophosphamide as an antigen has revealed that okra polysaccharides increased spleen index, splenocyte proliferation, and cytokines secretion [7].
We demonstrate that in early stages of acute phase, [IL-4.sup.-/-] knockout animals presented milder myocarditis with lower IFN-[gamma] production and higher in situ IL-10 production, despite Th1 cells increase in splenocyte general repertoire.
Cytokines detected by ELISA in splenocyte culture from immunized mice after stimulation with tachyzoite Toxoplasma Lysate Antigens (TLA) Number Immunization regimen (IFN-[gamma], pg/ml) Sig.
Moreover, the combined immunotherapy significantly increased the secretion of IFN-[gamma] and conversely diminished the secretion of IL-4 and TGF-[beta] in the splenocyte population compared to the splenocytes from the other groups.
Splenocyte cultures were prepared as described previously.[sup][19] Splenocytes were harvested from EAE mice (2–3 scores) 5 days after MOG immunization.
For the natural killer cell and splenocyte cell, RPMI 1640 medium was used instead of DMEM.
A mycelial lectin from Aspergillus nidulans microfungi induced an increase of NO production, and IFN[gamma] and IL-6 levels also enhanced in splenocyte cultures from treated Swiss albino mice groups.
Table 2: Splenocyte proliferative responses and flow cytometry analysis of T cell subclasses in spleen cells between the immunization and the controls.
(2008) Briefly, the splenocyte suspension in RPMI-1640 medium (4 x [10.sup.5] cells/ml), was preincubated in 96 well plates (200 [micro]l/well) with or without mitogens Con-A or LPS at a concentration of 5 and 10 [micro]g/ml, respectively) at 37 [degrees]C for 72 h in a 5% C[O.sub.2] incubator.
Nigella sativa modulates splenocyte proliferation, Th1/Th2 cytokine profile, macrophage function and NK anti-tumor activity.
The results demonstrated that CPP could promote the splenocyte proliferation, increase the activity of acid phosphatase in peritoneal macrophages and strengthen peritoneal macrophages to devour neutral red in vitro.