spiramycin


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spiramycin

A macrolide antibiotic that is similar to erythromycin, which has been used to treat toxoplasmosis and cryptosporidiosis in patients with AIDS. It is not FDA-approved and thus not available in the USA.
References in periodicals archive ?
Drug-susceptibility testing demonstrated that levofloxacin and spiramycin were effective on this strain.
Liu et al., "High concentrations of the antibiotic spiramycin in wastewater lead to high abundance of ammonia-oxidizing archaea in nitrifying populations," Environmental Science & Technology, vol.
Several drugs have been proposed for treatment including pyrimethamine, sulfadiazine, spiramycin, clindamycin, and trimethoprim-sulfamethoxazole [13].
Antibiotic Symbol [micro]g/ disc Clear zone diameter (mm) Ampicilin AM 10 08 R Streptomycin S 10 07 R Erythromycin E 15 15 R Kanamycin K 30 06 R Chloramphenicol C 30 22 S Pristinamycin PT 15 21 S Tobramycin TOB 10 09 R Clindamycin DA 2 23 S Spiramycin SP 100 17 I Amikacin AK 30 12 R Licomycin L 2 25 S Cefotaxim CTX 30 00 R Nalidixique acid NA 30 00 R Gentamicin CN 10 08 R R: resistance, I: intermidiate, and S: sensitive.
Otto, "Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes," Antimicrobial Agents and Chemotherapy, vol.
The standard of lincomycin, from the lincosamides family, as well as the standards from the macrolides (clindamycin, erythromycin, spiramycin, tilmicosin, and tylosin) and [beta]-lactams (cefazolin, cloxacillin, dicloxacillin, oxacillin, nafcillin, penicillin G, and penicillin V) families were purchased from Sigma Chemical Co.
(vi) Preparation of the antibiotic paste: 1.5 MIU Spiramycin pill and 250 mg Metronidazole were ground and mixed with distilled water (Figure 2).
Based on the inhibitory effect on the microbes in vitro of the 6 antimicrobial agents (including erythromycin, roxithromycin, azithromycin, acetyl spiramycin, clindamycin, and clarithromycin, at high and low concentrations) in the drug sensitivity plate, the microbial drug resistance was analyzed.
Brumpt, Simultaneous Determination of Metronidazole and Spiramycin I in Human Plasma, Saliva and Gingival Crevicular Fluid by LC-MS/MS, J Pharm Biomed Anal., 38, 298 (2005).
In vitro susceptibilities of oral bacteria isolate to spiramycin. Antimicrob Agents Chemothe, 1989; 33(11): 2016-2018
Minimal inhibitory concentrations of Pasteurella multocida was investigated and found highly resistant for spiramycin and fosfomycin [9].