Pattern 3: Blue Basaloid Proliferation in Dermis Spiradenoma
The painful tumor differential diagnosis has been described in the literature by the mnemonic "LEND AN EGG": leiomyoma, eccrine spiradenoma
, neuroma, dermatofibroma, angiolipoma, neurilemmoma, endometrioma, glomus tumor, and granular cell tumor.
Sonographic findings of an eccrine spiradenoma
: case report and literature review.
Bhattacharjee, "FDG PET/CT in malignant eccrine spiradenoma
," Clinical Nuclear Medicine, vol.
V Spagnolo et al., "Adenoid cystic carcinoma-like pattern in spiradenoma
and spiradenocylindroma: a rare feature in sporadic neoplasms and those associated with Brooke-Spiegler syndrome," The American Journal of Dermatopathology, vol.
Expression of p53 and TP53 mutational analysis in malignant neoplasms arising in preexisting spiradenoma
, cylindroma, and spiradenocylindroma, sporadic or associated with Brooke-Spiegler syndrome.
Carcinosarcoma arising in eccrine spiradenoma
. A clinicopathologic and immunohistochemical study of two cases.
Besides, the adnexa of the skin also give rise to appendage tumours like eccrine spiradenoma
and chondroid syringoma.
Other entities to be considered in the differential diagnosis include: inclusion cysts, giant cell tumor, foreign body reaction, eccrine spiradenoma
, osteoma cutis, trichilemmal cyst, hydrocystoma, basal cell carcinoma, calcification in lymph node, fat necrosis, pyogenic granuloma, lymphadenopathy, fibroxanthoma, chalazion and keratoacanthoma.1
On the basis of pathologic findings, the differential diagnoses include eccrine adenocarcinoma not otherwise specified (NOS), porocarcinoma, apocrine carcinoma, malignant chondroid syringoma, and eccrine spiradenoma
. The tumor in our patient would have been classified as an eccrine adenocarcinoma NOS if the benign eccrine acrospiroma component had not been present.
A case of eccrine spiradenoma
in a patient with neurofibromatosis.
Histochemistry of hidradenoma and eccrine spiradenoma
. J Invest Dermatol 1967; 49(2): 173-180.