spinocerebellar


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spinocerebellar

 [spi″no-ser″ĕ-bel´ar]
pertaining to the spinal cord and cerebellum.

spinocerebellar

(spī′nō-sĕr′ə-bĕl′ər)
adj.
Of, relating to, or involving both the spinal cord and the cerebellum: spinocerebellar degeneration.
References in periodicals archive ?
announced last July that the FDA had raised no objections to the company's Investigational New Drug (IND) application for a Phase 2 clinical trial in polyglutamine spinocerebellar ataxia (PolyQ SCA) conducted at clinical sites in the U.S.
To identify the Coriell cell line selected as the 2015 MGL2-09 spinocerebellar challenge sample, the records of the CAP/ACMG Committee were searched.
RNA gain-of-function in spinocerebellar ataxia type 8.
Genetic tests to exclude Friedreich ataxia and spinocerebellar ataxia 1, 2, 3, 6, 7, 12, 17, and 36 were performed.
Furthermore, symmetric signal abnormalities of bilateral MCPs might also be apparent in other clinical conditions including Wilson disease, hepatic encephalopathy, extrapontine myelinolysis, acute disseminated encephalomyelitis, leukodystrophy, olivopontocerebellar atrophy, spinocerebellar degeneration, toluene abuse, adrenoleukodystrophy, alcoholic liver disease, hypoglycemic coma, and progressive multifocal leukoencephalopathy.[6],[7],[9],[17] Although these lesions are rare, clinicians still need to carefully identify them using clinical and laboratory investigations combined with imaging findings to prevent misdiagnosis.
Saniona AB (STO:SANION), a biotechnology company in the field of ion channels, announced on Monday that its collaboration partner, Cadent Therapeutics, a precision neuroscience company, has initiated phase 1 trial for CAD-1883 for the treatment of spinocerebellar ataxia (SCA) and essential tremor.
Wave will provide Takeda the option to co-develop and co-commercialize programs in Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FID) and spinocerebellar ataxia type 3 (SCA3).
Spinocerebellar ataxia (SCA) comprises a family of autosomal dominant inherited disorders that result from progressive degeneration of the cerebellum and its associated systems [1].
Known causes of secondary RBD up to date are spinocerebellar ataxia [41], limbic encephalitis [42], brain tumors [42], multiple sclerosis [43], stroke [44], different antidepressants [45-47], alcohol [48], and barbiturate withdrawal [49].
Girisha, "Autosomal recessive spinocerebellar ataxia 20: Report of a new patient and review of literature," European Journal of Medical Genetics, vol.
In addition to EA2, the CACNA1A gene is implicated in at least two other autosomal dominant neurological disorders: familial hemiplegic migraine type 1 (FHM1) and spinocerebellar ataxia type 6 (SCA6).
Such patients are more likely to have additional neurological deficits as a result of involvement of other brainstem structures such as the spinothalamic, spinocerebellar, and pyramidal tracts [8].