Other members of this group include Huntington's disease, SCA 1, 2, 6, 7, and 17, dentatorubralpallidoluysian atrophy, and spinobulbar
Background: Amyotrophic lateral sclerosis (ALS) and some mimic disorders, such as distal-type cervical spondylotic amyotrophy (CSA), Hirayama disease (HD), and spinobulbar muscular atrophy (SBMA) may present with intrinsic hand muscle atrophy.
The median lifespan of ALS patients is 2–4 years from symptom onset.[sup] Generally, ALS is observed in middle-aged or older patients, as are cervical spondylosis and spinobulbar muscular atrophy (SBMA).
Sorenson, "Serum creatine kinase levels in spinobulbar
muscular atrophy and amyotrophic lateral sclerosis," Muscle and Nerve, vol.
[Multiple phenotypic manifestations of X-linked spinobulbar
Polyglutamine (PolyQ) diseases are inherited neurodegenerative disorders, such as Huntington's disease (HD), spinobulbar
muscular atrophy, and some types of spinocerebeller ataxia (SCA), including SCA3 Machado-Joseph disease (MJD).
The triplet repeat disorders results in at least 14 other progressive neurologic diseases including: fragile X syndrome, spinobulbar
muscular atrophy, myotonic dystrophy and Friedreich ataxia (Ensenauer, Reinke, Ackerman, Tester, Whitman, and Teffri, 2003; Martin, 1999).