Since the spindle fibers
pull the chromosomes apart and move them to opposite sides so that the cell may divide, if this did not happen the cells would not separate and therefore cause a mutation.
(1999) showed the highest pregnancy rate in pronuclear embryo cryopreservation and survivability of embryos was able to identify more accurately during thawing, as well as high implantation rate after thawing due to the absence of spindle fiber
. Consequently, non-disjunction of chromosome and chromosome abnormality were caused by spindle fiber
damage during the matured oocyte cryopreservation.
IIF patterns and diagnosis IIF Pattern n % Diagnosis n Cancer (esophageal, gastric, colon) 22 SAID 12 Midbody 49 0.49 Polyneuropathy 3 Infectious disease 3 Postmenopausal osteoporosis 1 Other pathologies 8 Autoimmune hepatitis/Primary Anti-actin 37 0.37 biliary cirrhosis/Chronic liver disease 36 Celiac disease 1 SAID 14 Centriole 29 0.29 Cerebrovascular disease 8 Other pathologies 7 SAID 2 Anti-golgi 21 0.21 Chronic liver disease 9 Infectious disease 4 Other pathologies 6 Infectious disease 5 Cancer 3 Spindle fibers
20 0.20 Vasculitis 2 Diabetes mellitus type 2 2 Autoimmune hepatitis 1 Other pathologies 7 Infectious disease 2 PCNA-like 9 0.09 Polyneuropathy 2 SAID 1 Other pathologies 4 Rods and rings 3 0.03 Chronic hepatitis C 3 SAID: Systemic autoimmune diseases.
In subsequent studies, Inoue and collaborators established the reversible assembly and disassembly of spindle fibers and fibrils in living cells when exposed to cold temperatures (Inoue, 1964), antimitotic drugs (Inoue.
The demonstration of spindle fibers in living cells.
In the former, the bivalents dispose parallel to the spindle fibers
, while in the latter the chromosomes are oriented perpendicularly to the fibers, so sometimes it is called reversed meiosis.
(C) The chromosomes line up along the spindle fibers
Asters disappear as a tetrapolar spindle is assembled; microtubules emanating from the four poles are organized into spindle fibers
at the surface of the tetrahedral nucleus (Fig.
The processes involved in biological models can be broken down into a sequence of "if/then" statements (e.g., if all chromosomes are attached to spindle fibers, then mitosis can proceed).
If all kinetochores are not attached to spindle fibers, then what would be observed in the cell?
In an effort to avoid injury, the nervous system monitors the intensity of a stretch with receptors called muscle spindle fibers
, located within the muscle itself.
We now demonstrate, at these General Scientific Meetings, through-focal and three-dimensionally reconstructed stereoscopic images of a free-swimming, pluteus-stage sea urchin embryo and the mitotic spindle fibers
within the two-cell stage of a dividing ctenophore egg.