spindle cell


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spin·dle cell

a fusiform cell, such as those in the deeper layers of the cerebral cortex.

spindle cell

n.
A spindle-shaped cell characteristic of certain tumors.

spindle cell

A generic term for an elonged and/or fusiform cell, regardless of origin.
 
Lineage
Mesenchymal, epithelial, lymphoproliferative; in general, mesenchymal spindle cells—e..g., fibroblasts and myofibroblasts—are benign and are normally found in stromal tissues; spindled epithelial cells are uncommon and usually seen in poorly differentiated squamous cell carcinoma, hairy cell leukaemia, and various sarcomas.

spin·dle cell

(spin'dĕl sel)
A fusiform cell, such as those in the deeper layers of the cerebral cortex.
References in periodicals archive ?
Strict diagnostic criteria should always be applied, but it may not be possible to classify a subset of spindle cell lesions with certainty.
Spindle cell pseudotumor of the brain associated with Mycobacterium haemophilum and Mycobacterium simiae mixed infection in a patient with AIDS: the first case report.
In cases of poorly differentiated or spindle cell variants of invasive SCC, immunohistochemical studies for p63 are widely regarded as useful in confirming squamous differentiation, with particular utility in the diagnostic differentiation from AFX and melanoma [7, 8].
Caption: Figure 4: (a, b) H&E stain at medium magnification show both discrete nodules of spindle cells (a) as well as individual spindle cells infiltrating among variably atrophic skeletal muscle fibers and collagenized stroma (b).
The HE-stain displayed a well demarcated proliferation of myofibroblastic spindle cells with irregular storiform arrangement and loosely admixed collagenous fibers.
Koutlas, "Spindle cell hemangioma (hemangioendothelioma) of the head and neck: case report of an unusual (or underdiagnosed) tumor," Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, vol.
A wide array of both benign and malignant spindle cell lesions can occasionally manifest in oral cavity and present a diagnostic challenge to oral pathologists owing to overlapping histopathological findings.
Other differential diagnoses include leiomyosarcoma, fibrosarcoma, rhabdomyosarcoma, malignant fibrous histiocytoma, spindle cell melanoma and metastatic transitional cell carcinoma.
Myofibroblastoma (MFB) is a rare benign spindle cell tumor of the breast.
"Cellular Angiofibroma: A Benign Neoplasm Distinct from Angiomyofibroblastoma and Spindle Cell Lipoma" American Journal of Surgical Pathology.
Based on the above features, a diagnosis of spindle cell tumor was made.