carcinoma of the head and neck region: Treatment and outcomes of 15 patients.
Strict diagnostic criteria should always be applied, but it may not be possible to classify a subset of spindle cell
lesions with certainty.
pseudotumor of the brain associated with Mycobacterium haemophilum and Mycobacterium simiae mixed infection in a patient with AIDS: the first case report.
In cases of poorly differentiated or spindle cell
variants of invasive SCC, immunohistochemical studies for p63 are widely regarded as useful in confirming squamous differentiation, with particular utility in the diagnostic differentiation from AFX and melanoma [7, 8].
Caption: Figure 4: (a, b) H&E stain at medium magnification show both discrete nodules of spindle cells
(a) as well as individual spindle cells
infiltrating among variably atrophic skeletal muscle fibers and collagenized stroma (b).
The HE-stain displayed a well demarcated proliferation of myofibroblastic spindle cells
with irregular storiform arrangement and loosely admixed collagenous fibers.
Koutlas, "Spindle cell
hemangioma (hemangioendothelioma) of the head and neck: case report of an unusual (or underdiagnosed) tumor," Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, vol.
A wide array of both benign and malignant spindle cell
lesions can occasionally manifest in oral cavity and present a diagnostic challenge to oral pathologists owing to overlapping histopathological findings.
Other differential diagnoses include leiomyosarcoma, fibrosarcoma, rhabdomyosarcoma, malignant fibrous histiocytoma, spindle cell
melanoma and metastatic transitional cell carcinoma.
Myofibroblastoma (MFB) is a rare benign spindle cell
tumor of the breast.
"Cellular Angiofibroma: A Benign Neoplasm Distinct from Angiomyofibroblastoma and Spindle Cell
Lipoma" American Journal of Surgical Pathology.
Based on the above features, a diagnosis of spindle cell
tumor was made.