S1PR2

(redirected from sphingosine-1-phosphate receptor 2)

S1PR2

A gene on chromosome 19p13.2 that encodes an EDG (endothelial differentiation, G protein-coupled) family receptor, which participates in sphingosine 1-phosphate-induced cell proliferation, survival and transcription activation.
References in periodicals archive ?
To observe the effect of DCA on the expression of sphingosine-1-phosphate receptor 2 (S1PR2), LPS-primed macrophage cell line J774A.1 was incubated with different dosage of DCA, and the results showed that DCA could dose and time dependently upregulate the mRNA level of S1PR2 compared to the LPS-treated alone group (Figures 1(a) and 1(b)).
Zhao et al., "Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes," Hepatology, vol.
Grant et al., "Bile acid-mediated sphingosine-1-phosphate receptor 2 signaling promotes neuroinflammation during hepatic encephalopathy in mice," Frontiers in Cellular Neuroscience, vol.
Yu, "Sphingosine-1-phosphate receptor 2 regulates proinflammatory cytokine production and osteoclastogenesis," PLoS One, vol.
Sphingosine-1-phosphate receptor 2 (S1PR2) is a member of G protein-coupled receptor, and it is related to the sphingosine-1-phosphate-induced cell proliferation (An et al., 2000; Adada et al., 2013).