While in the fourth generation, testis size being a minor quantity than partially of offspring of those mice consuming adequate Se (250-300 g/kg sodium selenite), and testis were observed to be bilaterally shrunken lacking mitotic action in spermatogonia
(Ufer and Wang, 2011).
The research team found that the number of undifferentiated spermatogonia
per seminiferous tubule increases steadily with age until about age 11, then rise sharply.
However, no significant difference was observed in the number of spermatogonia
(A and B), spermatocyte, round and long spermatids, and Sertoli cells between the experimental groups.
Prolonged dosing resulted in continued spermatocyte degeneration as well as maturation depletion of the spermatid population, leaving tubules containing only sustentacular cells, spermatogonia
and preleptotene spermatocytes.
Stage Cell types Size ([micro]m) Immature (I) Spermatogonia
10.35 [+ or -]0.11 Sertoli cells 10.63 [+ or -]0.46 Development (II) Spermatogonia
8.96 [+ or -]0.14 Spermatocytes Mature (III) Spermatogonia
Spermatocytes 7.73 [+ or -] 1.02 Spermatids 4.76 [+ or -] 0.14 acrosome Spermatozoa 11.16 [+ or -]0.2 spine TABLE 3.
brasiliana resulted from lesions and could be characterized as a generalized impairment of spermatogonia
maturation with exfoliation of degenerative cells and loss of seminiferous tubule cell layers (as observed in Table 2), including a loss of type A1 spermatogonia
These individuals presented primary growth oocytes as well as spermatogonia
, spermatocytes, and spermatozoids (Figs.
In the STs, predominant primary spermatocytes and spermatogonia
were stained as PCNA-positive in the control and L-cys groups.
Kallistem said it had managed to transform basic male fertility cells, called spermatogonia
, into mature sperm in test tubes.
The results of the microscopic examination showed no clear difference between the densities of spermatogonia
type A, primary spermatocytes at the pachytene stage, spermatids at the zygotene stage and spermatozoa in the seminiferous tubules of vaccinated (Figure 2Ba) and control lambs (Figure 2Bb) at week 30 after the primary immunization.
The Sertoli cells which proliferated and created a monolayer of feeder cells and spermatogonia
cells were colonized.
Three stages were present: (1) Regressed, seminiferous tubules contained mainly spermatogonia
and interspersed Sertoli cells; (2) Recrudescent, germ cell proliferation for the next period of sperm formation (spermiogenesis) had commenced.