Control group Table 3: The number of different testis cell types (x[10.sup.6]) Groups Spermatogonia A Spermatogonia B Sertoli cell Control 0.83[+ or -]0.06 0.16[+ or -]0.07 2.7[+ or -]0.2 BD1/2 0.83[+ or -]0.05 0.13[+ or -]0.05 2.5[+ or -]0.1 BD1/4 0.84[+ or -]0.05 0.18[+ or -]0.05 2.7[+ or -]0.3 Groups Primary Round Long spermatocyte spermatid spermatid
Control 12.1[+ or -]0.98 31.8[+ or -]2.49 30.9[+ or -]3.02 BD1/2 12.0[+ or -]0.80 31.0[+ or -]2.18 30.6[+ or -]2.66 BD1/4 12.4[+ or -]0.92 32.2[+ or -]2.20 32.1[+ or -]2.65 Groups Leydig cell Control 2.2[+ or -]0.02 BD1/2 2.5[+ or -]0.15 (**) BD1/4 2.1[+ or -]0.03 The values (n=5) are presented as mean[+ or -]SD.
Prolonged dosing resulted in continued spermatocyte degeneration as well as maturation depletion of the spermatid
population, leaving tubules containing only sustentacular cells, spermatogonia and preleptotene spermatocytes.
Testosterone promotes the conversion of round spermatids
between stages VII and VIII of the rat spermatogenic cycle.
demonstrated that the CDC25A protein was found in the cytoplasm of spermatogonial cells, pachytene spermatocytes stages, early to elongated spermatids
from testicular tissue samples (31).
The dynamic inverse relationship between proteases and protease inhibitors is indispensable for Sertoli-germ cell junction disassembly to release elongated spermatids
into the tubule lumen .
This stage is characterized by the absence of elongated spermatids
. The prominent cell was an early generation of spermatids
with round nuclei found in the upper layer of seminiferous epithelium.
PSC = primary spermatocyte; SSC = secondary spermatocyte; ST = spermatid
; SPZ = spermatozoa; SZ = spermatozeugmata.
The groups of stages I-VI (one spermatids
generation), VII-VIII (spermatozoa), IXXIII (two generations of spermatids
) and XIV (secondary spermatocyte) of the seminiferous epithelium cycle (Leblond & Clemont, 1952) were identified under a light microscope (Leica DMLS) at x 200 magnification.
Some abundant spermatocytes, ripe oocytes with a large smaller spermatids
, and nucleus may be observed ripe spermatozoa with free in the lumen.
(a) The control rabbit showing normal appearance of spermatogenic cells; spermatogonia (sg), primary spermatocyte (ps), spermatid
(sp), and Sertoli cells (sc).
The germinal epithelium consists of spermatogonia resting on the basement membrane, large primary spermatocytes, early or rounded spermatids
with acrosomal caps, and late or elongated spermatids
(Figures 3 and 4).
Reproductive classes: The reproductive stages of the spermatogenesis (spermatogonia, primary and secondary spermatocytes, spermatids
and spermatozoa) are a commonly used indicator for depicting reproductive cycles (Grier & Taylor, 1998; Wallace & Selman 1989; Uribe et al.