spectrum bias


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spectrum bias

Variation in the performance of a diagnostic test due to its application to people of differing ages, genders, nationalities, or specific disease manifestations. A test's sensitivity and specificity may increase or decrease, depending on the population to which it is applied.
Synonym: case-mix bias
References in periodicals archive ?
As described in the companion review by Schmidt and Factor in this issue, assessment of spectrum bias depends on a comparison of patient populations.
Similarly, an analogous plot was used to identify spectrum bias.
A similar plot was used to examine the group of studies for possible spectrum bias.
Spectrum bias in musculoskeletal medicine: how we can disagree and both be right?
With differences as large as this, the influence of spectrum bias on the results might need to be considered.
Spectrum bias in the evaluation of diagnostic tests: lessons from the rapid dipstick test for urinary tract infection.
3) quantified the effect of spectrum bias, which arises when clinicians enroll very ill patients and compare their results with those from healthy controls.
The metaanalysis focused the appraisal of study quality on the potential for differential reference standard bias (10) and spectrum bias (11).
Thus, it can be speculated that because of spectrum bias, the diagnostic indexes derived in this metaanalysis will be slightly different from those that will be observed in real practice.
The effect of spectrum bias on the utility of magnetic resonance imaging and evoked potentials in the diagnosis of suspected multiple sclerosis.
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