spectinomycin


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spectinomycin

 [spek″tĭ-no-mi´sin]
an antibiotic derived from Streptomyces spectabilis, used as the hydrochloride salt in treatment of gonorrhea.

spectinomycin

(spĕk′tə-nō-mī′sĭn)
n.
A broad-spectrum antibiotic, C14H24N2O7, obtained from a species of gram-negative bacteria (Streptomyces spectabilis) or produced synthetically and used in its hydrochloride form especially in the treatment of penicillin-resistant gonorrhea.

spectinomycin

An aminocyclitol antibiotic used by intramuscular injection to treat GONORRHOEA. The drug is on the WHO official list. Users should avoid Botox treatments.
References in periodicals archive ?
Sugarcane leaf roll discs were cultured on the callus induction medium (MS3) supplemented with different levels of the antibiotics spectinomycin (0, 25, 50, 100, 150, 200, 250, 300, 350, 400, 450 and 500 mg/L), streptomycin (0, 25, 50, 100, 150, 200, 250, 300, 350 and 400 mg/L) and kanamycin (0, 25, 50, 100, 150, 200, 250, 300, 350 and 400 mg/L).
ceftriaxone and spectinomycin in the treatment of uncomplicated
All subsequent antibiotic resistance analyses were performed at the following concentrations: ampicillin (100 [micro].g/ml), chloramphenicol (10 [micro]g/ml), erythromycin (100 [micro]g/ml), neomycin (50 [micro]g/ml), oxytetracyclin (100 [micro]g/ml), spectinomycin dihydrochloride (10 [micro]g/ml), streptomycin sulfate (100 [micro]g/ml), and tetracycline hydrochloride (10 [micro]g/ml).
Spectinomycin is an alternative antimicrobial for women who cannot take a cephalosporin (or penicillin).
E.coli from Humans, Cattle, or Deer were collected, isolated, and tested for growth in the presence of various antibiotics (ampicillin, chloramphenicol, erythromycin, neomycin, oxytetracycline, spectinomycin dihydrochloride, streptomycin sulfate, and tetracycline hydrochloride) and these results were used to develop discriminant functions that correctly categorized E.coli of unknown origin with high accuracy.
The antimicrobial susceptibility testing panel should, at a minimum, include a fluoroquinolone, ceftriaxone, spectinomycin, azithromycin, and any other drugs in local use for gonorrhea treatment.
Spectinomycin is no longer being produced in the United States.
Another treatment option for patients at high risk of a quinolone-resistant infection is an injection of spectinomycin, said Dr.
Mutants were selected in KB agar supplemented with spectinomycin (25 [micro]g/ml).
Aminoglycosides approved for use in food animals in the United States include dihydostreptomycin, efrotomycin, hygromycin B, neomycin, spectinomycin, streptomycin, and apramycin (37).
The distribution of resistance to ampicillin, chloramphenicol, erythromycin, neomycin, oxytetracycline, spectinomycin, vancomycin, tetracycline, and streptomycin among fecal coliforms was investigated as part of a continuation of an observation of the bacteriological content of Dry Creek in Perry County.
The recommended treatment options for persons who might have acquired infection in those areas are cefixime (7), ceftriaxone, or spectinomycin. To select appropriate gonorrhea treatment in areas outside Hawaii and California, clinicians should ask suspected gonorrhea patients about their recent travel history and that of their sex partners (8).