Causing spasms.
[spasmo- + G. -gen, producing]
Farlex Partner Medical Dictionary © Farlex 2012
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For the Lamiaceae family, there were few studies which showed activity of the same species on uterine muscle, but with spasmogenic or uterotonic activity, that is, with opposing goals for this study (Ladeji et al., 2005; Chen et al., 2000; Gruber and O'Brien, 2011; Kamatenesi-Mugisha and Oryem-Origa, 2007).
Spasmogenic and spasmolytic activity of rind of Punica granatum Linn.
Eclipta alba shows versatile pharmacological effects that include hair growth, antimicrobial, antioxidant, anti-inflammatory, analgesic, antinociceptive, antileprotic, antihaemorrhagic, antimyotoxic, antiviral, antihepatotoxic, diuretic, hypotensive, hypocholesterolemic, hypotensive, immunomodulatory, nootropic, ovicidal, and spasmogenic activity [24-34].
Other biological activities, such as spasmogenic, immunostimulatory, anti-inflammatory, antihemorrhagic, antihyperglycemic, antihyperlipidemic, antiulcer, antidiarrheal, and antioxidant activities, were also investigated in different species [9].
The spasmogenic and spasmolytic activities of lavandula Stoechas are mediated through muscarinic receptor stimulation and calcium channel blockade.
Ginger extract contains a cholinergic and spasmogenic component, which provides a mechanistic insight for the prokinetic action of ginger.(40)
Factor C3f is a spasmogenic fragment released from C3b by factors I and H: the heptadeca-peptide C3f was synthesized and characterized.
The antagonistic effect of urantide is highly selective, only acting against the vasoconstrictive effect of U-II by ignoring the responses produced by different spasmogenic compounds, such as noradrenaline and ET-1 [26, 27].
Data show that Cydonia oblonga possesses spasmogenic effect mediated through cholinergic pathway, while Ca++ antagonist like mechanism is found responsible for its spasmolytic activity, thus provides justification for the medicinal use of the plant in gut and airways disorders.
C3a has spasmogenic activities [20] and increases microvascular permeability [5].
For example: spasmogenic effect of crude saponin fraction isolated form Panax ginseng was completely inhibited by atropine (Takagi et al., 1972); radish extract, rich in saponins, stimulated GI motility in vitro and in vivo and its pharmacological activity was, at least partly, mediated by activation of muscarinic acetylcholinergic mechanism (Jung et al.