sparteine

spar·te·ine

(spar'tē-ēn, -tē-in),

An alkaloid obtained from scoparius, Cytisus scoparius and Lupinus luteus; sparteine sulfate was used as an oxytocic drug.

Synonym(s): lupinidine

(spär′tē-ēn′, -ĭn)

A bitter, poisonous, liquid alkaloid, C₁₅H₂₆N₂, that is present in the broom Cytisus scoparius and in the seeds of several species of Lupinus.

a toxic alkaloid found in Spanish broom and lupins. It causes paralysis of sympathetic ganglia and motor nerve endings.

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References in periodicals archive ?

Defective N-oxidation of sparteine in man: a new phamtacogenetic defect.

Chromosomal assignment of human cytochrome P450 (debrisoquine/ sparteine type) to chromosome 22.

Evidence for a new variant CYP2D6 allele CYP2D6J in a Japanese population associated with lower in vivo rates of sparteine metabolism.

An additional allelic variant of the CYP2D6 gene causing impaired metabolism of sparteine.

Substantial rise in sparteine metabolic ratio during haloperidol treatment.

Imipramine metabolism in relation to the sparteine and mephenytoin oxidation polymorphisms--a population study.

First-pass metabolism of imipramine and desipramine: impact of the sparteine oxidation phenotype.

Polymorphic oxidation of sparteine and debrisoquine: related pharmacogenetic entities.

Evidence for a new variant CYP2D6 allele CYP2D6J in a Japanese population with lower in vivo rates of sparteine metabolism.

Pharmacokinetics of citalopram in relation to the sparteine and the mephenytoin oxidation polymorphisms.

Single-dose kinetics of clomipramine: relationship to the sparteine and Smephenytoin oxidation polymorphisms.