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glycine max(trade name),
soy protein(trade name),
Menopausal symptoms.Prevention of breast, lung, endometrial, thyroid and prostate cancers.Hyperlipidemia.
Soy is the most significant dietary source of isoflavones. Pharmacologic effects of soy include lowering of homocysteine levels, inhibition of platelet aggregation, lowering of blood pressure, inhibition of cholesterol absorption in the small bowel and lowering of LDL cholesterol. Soy isoflavones also have antioxidant, antiproliferative and estrogenic effects.
Decreased hot flashes in menopausal women.
Metabolism and Excretion: Unknown
Contraindicated in: Hypersensitivity.End stage renal disease.Urinary bladder cancer (may increase risk).
Use Cautiously in: Nephrolithiasis.Hypothyroidism.
Adverse Reactions/Side Effects
- gastrointestinal upset
InteractionsAntibiotics may ↓ effects of soy. May inhibit effects of estrogens and tamoxifen.May ↑ risk of hypertensive crisis with MAO inhibitors.May ↓ INR of patients taking warfarin. None.
Oral (Adults) 35–120 mg/day.
- Monitor blood pressure prior to and periodically during therapy.
- Hypercholesterolemia: Obtain a diet history, especially with regard to fat consumption.
- Menopausal symptoms: Assess the frequency and intensity of hot flashes prior to and periodically during therapy.
- Lab Test Considerations: Monitor blood glucose, lipid profile, hormones, and thyroid function before and periodically during therapy.
Potential Nursing DiagnosesDeficient knowledge, related to diet and medication regimen (Patient/Family Teaching)
- Oral: Administer as directed.
- Instruct patient to take as directed.
- Instruct patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
- Decrease in frequency and intensity of hot flashes.
- Reduction in serum cholesterol levels.
A type of vegetable protein found in food products derived from soybeans. Soy-based foods also contain fiber, flavones, phytoestrogens, and other potentially beneficial components. See: soy milk; tofu
See also: protein