cells of the pituitary gland secrete growth hormone whose secretion continues throughout life, although varies based on growth period of humans.
The growth rate is dependent upon the amount of GH secreted by the pituitary somatotropes
with the higher concentrations of GH inducing higher rate of growth in humans (Rogol, 2010).
Adiponectin directly induces GH secretion from somatotropes
Based on murine expression of IGSF1 protein in thyrotropes, somatotropes
, and lactotropes in the pituitary gland, a role for IGSF1 in pituitary GH production and/or secretion appears likely.
Responsiveness of chicken embryonic somatotropes
to somatostatin (SRIF) and IGF-I.
In the current report, using an enzyme-linked immunosorbent assay for GH detection and whole-cell patch-clamp recordings, we assessed the long-term actions of such regulatory factors on voltage-activated [Ca.sup.2+] currents in bovine somatotropes
(BS) separated on a Percoll gradient and detected by immunohistochemistry.
Cordoba-Chacon et al., "Metabolic impact of adult-onset, isolated, growth hormone deficiency (AOiGHD) due to destruction of pituitary somatotropes
," PLoS ONE, vol.
Our results suggest that resistin might regulate GHRH or SRIF secretion to obtain GH release, or as it has been reported previously, resistin could act directly over somatotropes
to regulate GH release .
However, not all kisspeptin positive cells within the pituitary were also LH[beta] positive; therefore, the observed reduction in KiSS-1 mRNA expression may also affect other pituitary cell types, including somatotropes
, lactotropes, and gonadotropes that specifically synthesize FSH.
Board 11 SPERM PROTEIN SP22 IN SOMATOTROPES
GH accounts for 30-40% of the cells of the pituitary gland where the somatotropes
produce and store it.
Endogenous hypothalamic somatostatins differentially regulate growth hormone secretion from goldfish pituitary somatotropes