somatostatins


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somatostatins

Tetradecapeptides widely distributed in the body, that inhibits the secretion of many HORMONES and NEUROTRANSMITTERS. Somatostatins are secreted in the hypothalamus, elsewhere in the brain, the gastrointestinal tract, pancreas, retina, spinal cord and various endocrine glands. They have been suggested as antidotes to growth hormone in conditions such as ACROMEGALY but have a very short duration of action and their use results in rebound over-secretion. The drug octreotide (Sandostatin) is a somatostatin analogue.
References in periodicals archive ?
Endogenous hypothalamic somatostatins differentially regulate growth hormone secretion from goldfish pituitary somatotropes in vitro.
Somatostatin (SS) is a neuropeptide family which effects growth, development and metabolism.
Coilia nasus, Somatostatin, Molecular cloning, Growth hormone, Cortistatin, Embryonic development.
The neuropeptide somatostatin (SS) was isolated from ovine hypothalamus firstly.
Distribution of somatostatin immunoreactive neurons and fibres in the central nervous system of a chondrostean, the Siberian sturgeon (Acipenser baeri).
Differential expression of two somatostatin genes during zebrafish embryonic development.
Molecular and expression characterization of two somatostatin genes in the Chinese sturgeon, Acipenser sinensis.
1997) Nutritional state affects somatostatin gene expression in rainbow trout.
Specialists in endocrinology, physiology, oncology, pathology, and nuclear medicine mainly from Europe survey analogues to the hormone somatostatin and their use in tumor diagnosis and therapy.