Recently, NT-proSST has been shown to be a potential marker for acute heart failure and mortality in an unselected patient cohort presented to an emergency department (5, 16) and for the diagnosis of
somatostatinoma in humans (17).
The medical subject Headings indexing system refers to "islet cell carcinoma", which is subdivided into gastrinoma, glucagonoma,
somatostatinoma and VIPoma.
These tumors are classified according to the predominant hormone of oversecretion: insulinoma, gastrinoma, vasoactive intestinal peptide-secreting tumors (VIPoma), glucagonoma,
somatostatinoma, and growth-hormone-releasing factor-secreting tumors (GRFomas).
Somatostatinoma of the duodenum with psammoma bodies (arrows in [A] point to psammomatous calcifications).
Calcification have been described in various neoplasm associated with hormone production including duodenal
Somatostatinoma, carcinoid tumour, prolactinoma, calcifying Sertoli cell tumour and gonadoblastoma [3].
Pancreatic tumors classification * Primary tumors Exocrine Ductal adenocarcinoma Serous cystic tumor Mucinous cystic tumor Solid-pseudopapillarymucinous tumor Acinar cell carcinoma Anaplastic carcinoma Pancreatoblastoma Endocrine Insulinoma Gastrinoma Glucagonoma Vipoma
Somatostatinoma Nonhyperfunctiong tumor Nonepithelial tumor Lymphoma Teratoma Lymphangioma Lipoma Neural tumors Secondary tumors * Table data adapted from Solcia E, Capella C, Kloppel G.
43,44) These glandular carcinoids often contain psammoma bodies but do not produce the
somatostatinoma syndrome as reported in patents with pancreatic endocrine D cell tumors.
Composite tumor of mucinous cystadenoma and
somatostatinoma of the kidney.
The 2 exceptions are the stroma with amyloid deposits identifying insulinoma and the glandular pattern with psammoma bodies identifying
somatostatinoma.
Pituitary tumors in budgerigars (Melopsittacus undulatus) secrete somatostatin, and
somatostatinomas in some species, including humans and bearded dragons (Pogona vitticeps), may be associated with hyperglycemia.
79) For functioning tumors, insulinomas have an indolent clinical behavior, whereas gastrinomas, glucagonomas, and
somatostatinomas are associated with a high malignant potential.
