SSTR2

(redirected from somatostatin receptor 2)

SSTR2

A gene on chromosome 17q24 that encodes a G protein-coupled somatostatin receptor for somatostatin-14 and -28. It interacts with SHANK1 and is expressed in the brain and kidneys.
References in periodicals archive ?
The company's lead pentarin clinical drug candidate, PEN-221, targets the somatostatin receptor 2 (SSTR2) for treatment of patients with tumors that express SSTR2 including neuroendocrine, small cell lung, and other cancers.
Planned development activities include completing Phase I dose-escalation and safety studies of PEN-221, a miniaturized conjugate targeting somatostatin receptor 2 (SSTR2), which is expressed in neuroendocrine and small cell lung cancers, and initiating and advancing its Phase 2A studies.
The company's lead Pentarin drug candidate, PEN-221, is a miniaturized drug conjugate that targets the somatostatin receptor 2 (SSTR2) for treatment of patients with neuroendocrine and small cell lung cancers.