In the United States, only somatic cell gene therapy
has been approved for human clinical trials.
Somatic cell gene therapy, as it is called, is an application of recombinant DNA technology.
So the challenge is to apply current statutory authority to somatic cell gene therapy and apply it just as you would with antibiotics.
Somatic cell gene therapy
is the alteration of human somatic cells in order to treat a specific disorder.
Reason: Why haven't researchers been more successful in using somatic cell gene therapy
- replacing defective genes in a patient's tissues with normal versions - to cure genetic diseases such as cystic fibrosis?
In general, the ethical analysis of somatic cell gene therapy
follows in broad outline an analysis similar to that of the introduction of any new medical therapy.
Indeed, what is known as somatic cell gene therapy
is becoming a standard method for treating both kinds of diseases.
He notes the difference in attitude "toward negative and positive forms of engineering" and states that the former "and less dubious procedure is sometimes referred to as somatic cell gene therapy
Somatic Cell Gene Therapy
- Gene therapy that alters a specific trait or function by the introduction of an effective new gene into a specific class of somatic cells (body cells).
We analyzed the risk/benefit determination for somatic cell gene therapy
and proposed three questions that need to have been answered from prior animal experimentation: Can the new gene be inserted stably into the correct target cells?
One day, somatic cell gene therapy
also may help those with cancers that don't respond to traditional methods.
Two of the other conclusions of the Rome meeting--classifying somatic cell gene therapy
with other medical experimentation, while doubting that "medical indications [or] ethical justifications" now exist for intentional manipulation of human germ-line-cells--are also consistent with the conclusions of the President's Commission and of such other U.S.